mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses

ABSTRACT Jorge Amich studies several aspects of sulfur and nitrogen metabolism in Aspergillus fumigatus, with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how “Sub-Telomere Directed Gene Expression during Initi...

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Autor principal:	Jorge Amich
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	fungal virulence in vivo transcriptomics Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/9cccd22660e64d0e8de7bfdc42bb2c47
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spelling	oai:doaj.org-article:9cccd22660e64d0e8de7bfdc42bb2c472021-11-15T15:22:27ZmSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses10.1128/mSphere.00566-192379-5042https://doaj.org/article/9cccd22660e64d0e8de7bfdc42bb2c472019-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00566-19https://doaj.org/toc/2379-5042ABSTRACT Jorge Amich studies several aspects of sulfur and nitrogen metabolism in Aspergillus fumigatus, with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how “Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis” (A. McDonagh, N. D. Fedorova, J. Crabtree, Y. Yu, S. Kim, et al., PLoS Pathog 4:e1000154, 2008, https://doi.org/10.1371/journal.ppat.1000154) impacted his thinking about in vivo metabolism and how to investigate it.Jorge AmichAmerican Society for Microbiologyarticlefungal virulencein vivo transcriptomicsMicrobiologyQR1-502ENmSphere, Vol 4, Iss 4 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	fungal virulence in vivo transcriptomics Microbiology QR1-502
spellingShingle	fungal virulence in vivo transcriptomics Microbiology QR1-502 Jorge Amich mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
description	ABSTRACT Jorge Amich studies several aspects of sulfur and nitrogen metabolism in Aspergillus fumigatus, with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how “Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis” (A. McDonagh, N. D. Fedorova, J. Crabtree, Y. Yu, S. Kim, et al., PLoS Pathog 4:e1000154, 2008, https://doi.org/10.1371/journal.ppat.1000154) impacted his thinking about in vivo metabolism and how to investigate it.
format	article
author	Jorge Amich
author_facet	Jorge Amich
author_sort	Jorge Amich
title	mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
title_short	mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
title_full	mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
title_fullStr	mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
title_full_unstemmed	mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
title_sort	msphere of influence: the importance of metabolism for pathogen adaptation to host-imposed stresses
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/9cccd22660e64d0e8de7bfdc42bb2c47
work_keys_str_mv	AT jorgeamich msphereofinfluencetheimportanceofmetabolismforpathogenadaptationtohostimposedstresses
_version_	1718427966790172672

mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses

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