Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites
Abstract Activation-induced cytidine deaminase (AID) triggers antibody diversification in B cells by catalysing deamination and subsequently mutating immunoglobulin (Ig) genes. Association of AID with RNA Pol II and occurrence of epigenetic changes during Ig gene diversification suggest participatio...
Guardado en:
Autores principales: | Virginia C. Rodríguez-Cortez, Paloma Martínez-Redondo, Francesc Català-Moll, Javier Rodríguez-Ubreva, Antonio Garcia-Gomez, Ganesh Poorani-Subramani, Laura Ciudad, Henar Hernando, Arantxa Pérez-García, Carlos Company, José M. Urquiza, Almudena R. Ramiro, Javier M. Di Noia, Alejandro Vaquero, Esteban Ballestar |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9cd2b9c633a74c8184f98b09354dec72 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase.
por: Iñigo Narvaiza, et al.
Publicado: (2009) -
Expanding C–T base editing toolkit with diversified cytidine deaminases
por: Tian-Lin Cheng, et al.
Publicado: (2019) -
AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates
por: Mei-Chen Liu, et al.
Publicado: (2018) -
Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.
por: Yuko Arioka, et al.
Publicado: (2012) -
Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus
por: Danielle Perez-Bercoff, et al.
Publicado: (2021)