p190RhoGAP proteins contain pseudoGTPase domains

A growing number of ‘pseudoenzymes’ with a regulatory role in signal transduction processes but without catalytic activity are being identified. Here, the authors identify two pseudoGTPase domains in p190RhoGAP, characterize them biochemically and structurally and show that they influence RhoGAP act...

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Auteurs principaux: Amy L. Stiegler, Titus J. Boggon
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/9cd51f99991242e7909c8e191046ed0e
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