Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry

Abstract The contribution of paternal obesity to pregnancy outcomes has been little described. Our aims were to determine whether the effect of an antenatal maternal dietary and lifestyle intervention among women who are overweight or obese on newborn adiposity, was modified by paternal obesity. We...

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Autores principales:	Jodie M. Dodd, Lodewyk E. Du Plessis, Andrea R. Deussen, Rosalie M. Grivell, Lisa N. Yelland, Jennie Louise, Andrew J. Mcphee, Jeffrey S. Robinson, Julie A. Owens
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9cec868bdb9d4ed592b8db02e7e58fda
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spelling	oai:doaj.org-article:9cec868bdb9d4ed592b8db02e7e58fda2021-12-02T15:06:10ZPaternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry10.1038/s41598-017-01672-w2045-2322https://doaj.org/article/9cec868bdb9d4ed592b8db02e7e58fda2017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-01672-whttps://doaj.org/toc/2045-2322Abstract The contribution of paternal obesity to pregnancy outcomes has been little described. Our aims were to determine whether the effect of an antenatal maternal dietary and lifestyle intervention among women who are overweight or obese on newborn adiposity, was modified by paternal obesity. We conducted a secondary analysis of a multicenter randomised trial. Pregnant women with BMI ≥25 kg/m2 received either Lifestyle Advice or Standard Care. Paternal anthropometric measures included height, weight, BMI; waist, hip, calf and mid-upper arm circumferences; biceps and calf skinfold thickness measurements (SFTM); and percentage body fat. Newborn anthropometric outcomes included length; weight; head, arm, abdominal, and chest circumferences; biceps, triceps, subscapular, suprailiac, thigh, and lateral abdominal wall SFTM; and percentage body fat. The effect of an antenatal maternal dietary and lifestyle intervention among women who were overweight or obese on neonatal anthropometric measures, was significantly modified by paternal BMI ≥35.0 kg/m2, with a significantly smaller infant triceps, suprailiac, and thigh SFTM, and percent fat mass, compared with that observed in offspring of lean fathers. Further research is required to determine whether our observed associations are causal, and whether paternal weight loss prior to conception is a potential strategy to reduce the intergenerational effects of obesity.Jodie M. DoddLodewyk E. Du PlessisAndrea R. DeussenRosalie M. GrivellLisa N. YellandJennie LouiseAndrew J. McpheeJeffrey S. RobinsonJulie A. OwensNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jodie M. Dodd Lodewyk E. Du Plessis Andrea R. Deussen Rosalie M. Grivell Lisa N. Yelland Jennie Louise Andrew J. Mcphee Jeffrey S. Robinson Julie A. Owens Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
description	Abstract The contribution of paternal obesity to pregnancy outcomes has been little described. Our aims were to determine whether the effect of an antenatal maternal dietary and lifestyle intervention among women who are overweight or obese on newborn adiposity, was modified by paternal obesity. We conducted a secondary analysis of a multicenter randomised trial. Pregnant women with BMI ≥25 kg/m2 received either Lifestyle Advice or Standard Care. Paternal anthropometric measures included height, weight, BMI; waist, hip, calf and mid-upper arm circumferences; biceps and calf skinfold thickness measurements (SFTM); and percentage body fat. Newborn anthropometric outcomes included length; weight; head, arm, abdominal, and chest circumferences; biceps, triceps, subscapular, suprailiac, thigh, and lateral abdominal wall SFTM; and percentage body fat. The effect of an antenatal maternal dietary and lifestyle intervention among women who were overweight or obese on neonatal anthropometric measures, was significantly modified by paternal BMI ≥35.0 kg/m2, with a significantly smaller infant triceps, suprailiac, and thigh SFTM, and percent fat mass, compared with that observed in offspring of lean fathers. Further research is required to determine whether our observed associations are causal, and whether paternal weight loss prior to conception is a potential strategy to reduce the intergenerational effects of obesity.
format	article
author	Jodie M. Dodd Lodewyk E. Du Plessis Andrea R. Deussen Rosalie M. Grivell Lisa N. Yelland Jennie Louise Andrew J. Mcphee Jeffrey S. Robinson Julie A. Owens
author_facet	Jodie M. Dodd Lodewyk E. Du Plessis Andrea R. Deussen Rosalie M. Grivell Lisa N. Yelland Jennie Louise Andrew J. Mcphee Jeffrey S. Robinson Julie A. Owens
author_sort	Jodie M. Dodd
title	Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
title_short	Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
title_full	Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
title_fullStr	Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
title_full_unstemmed	Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
title_sort	paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9cec868bdb9d4ed592b8db02e7e58fda
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Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry

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