Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
TAR DNA-binding protein 43 (TDP-43) is a major component within ubiquitin-positive inclusions of a number of neurodegenerative diseases that increasingly are considered as TDP-43 proteinopathies. Identities of other inclusion proteins associated with TDP-43 aggregation remain poorly defined. In this...
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Autores principales: | Eric B Dammer, Claudia Fallini, Yair M Gozal, Duc M Duong, Wilfried Rossoll, Ping Xu, James J Lah, Allan I Levey, Junmin Peng, Gary J Bassell, Nicholas T Seyfried |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/9cf44cf929ca48b18b142527619bc7da |
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