Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes

Viruses are the most important cause of infectious encephalitis in mammals worldwide; several thousand people, primarily the very young and the elderly, are impacted annually, and few therapies are reliably successful once neuroinvasion has occurred. To understand how viruses contribute to neuropat...

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Autores principales: Katrien C. K. Poelaert, Riley M. Williams, Christine M. Matullo, Glenn F. Rall
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/9cfa63f7f98a425295b1b6acaf3c2c1e
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spelling oai:doaj.org-article:9cfa63f7f98a425295b1b6acaf3c2c1e2021-11-03T18:56:09ZNoncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes2150-751110.1128/mBio.00288-21https://doaj.org/article/9cfa63f7f98a425295b1b6acaf3c2c1e2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00288-21https://doaj.org/toc/2150-7511 Viruses are the most important cause of infectious encephalitis in mammals worldwide; several thousand people, primarily the very young and the elderly, are impacted annually, and few therapies are reliably successful once neuroinvasion has occurred. To understand how viruses contribute to neuropathology, and to develop tools to prevent or ameliorate such infections, it is crucial to define if and how viruses disseminate among the different cell populations within the highly complex central nervous system.Katrien C. K. PoelaertRiley M. WilliamsChristine M. MatulloGlenn F. RallAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Katrien C. K. Poelaert
Riley M. Williams
Christine M. Matullo
Glenn F. Rall
Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes
description Viruses are the most important cause of infectious encephalitis in mammals worldwide; several thousand people, primarily the very young and the elderly, are impacted annually, and few therapies are reliably successful once neuroinvasion has occurred. To understand how viruses contribute to neuropathology, and to develop tools to prevent or ameliorate such infections, it is crucial to define if and how viruses disseminate among the different cell populations within the highly complex central nervous system.
format article
author Katrien C. K. Poelaert
Riley M. Williams
Christine M. Matullo
Glenn F. Rall
author_facet Katrien C. K. Poelaert
Riley M. Williams
Christine M. Matullo
Glenn F. Rall
author_sort Katrien C. K. Poelaert
title Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes
title_short Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes
title_full Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes
title_fullStr Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes
title_full_unstemmed Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes
title_sort noncanonical transmission of a measles virus vaccine strain from neurons to astrocytes
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/9cfa63f7f98a425295b1b6acaf3c2c1e
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AT christinemmatullo noncanonicaltransmissionofameaslesvirusvaccinestrainfromneuronstoastrocytes
AT glennfrall noncanonicaltransmissionofameaslesvirusvaccinestrainfromneuronstoastrocytes
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