Adult pulmonary blastoma in an adult with urothelial cancer: A case report

Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25–0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults.Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are...

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Autores principales: Shailesh Kolekar, Kristrun Gudmundsdottir, Karen Ege Olsen, Pradeesh Sivapalan, Paul Frost Clementsen, Uffe Bodtger
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Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/9d0d486c59a04d33bef51e935663b108
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spelling oai:doaj.org-article:9d0d486c59a04d33bef51e935663b1082021-11-12T04:32:52ZAdult pulmonary blastoma in an adult with urothelial cancer: A case report2213-007110.1016/j.rmcr.2021.101556https://doaj.org/article/9d0d486c59a04d33bef51e935663b1082021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2213007121002185https://doaj.org/toc/2213-0071Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25–0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults.Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are unclear.People with DICER1 syndrome commonly develop Pulmonary blastoma and do have concomitant or previous history of benign or malignant tumours in extra pulmonary site like kidney, thyroid, ovary cervix testicle and eye.As per our knowledge, this is the first case of adult pulmonary blastoma previously diagnosed with urothelial cancer and a strong familial predilection of malignancy, with negative genetic test for DICER1 mutations.Shailesh KolekarKristrun GudmundsdottirKaren Ege OlsenPradeesh SivapalanPaul Frost ClementsenUffe BodtgerElsevierarticlePulmonary blastomaDICER1Urothelial cancerDiseases of the respiratory systemRC705-779ENRespiratory Medicine Case Reports, Vol 34, Iss , Pp 101556- (2021)
institution DOAJ
collection DOAJ
language EN
topic Pulmonary blastoma
DICER1
Urothelial cancer
Diseases of the respiratory system
RC705-779
spellingShingle Pulmonary blastoma
DICER1
Urothelial cancer
Diseases of the respiratory system
RC705-779
Shailesh Kolekar
Kristrun Gudmundsdottir
Karen Ege Olsen
Pradeesh Sivapalan
Paul Frost Clementsen
Uffe Bodtger
Adult pulmonary blastoma in an adult with urothelial cancer: A case report
description Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25–0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults.Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are unclear.People with DICER1 syndrome commonly develop Pulmonary blastoma and do have concomitant or previous history of benign or malignant tumours in extra pulmonary site like kidney, thyroid, ovary cervix testicle and eye.As per our knowledge, this is the first case of adult pulmonary blastoma previously diagnosed with urothelial cancer and a strong familial predilection of malignancy, with negative genetic test for DICER1 mutations.
format article
author Shailesh Kolekar
Kristrun Gudmundsdottir
Karen Ege Olsen
Pradeesh Sivapalan
Paul Frost Clementsen
Uffe Bodtger
author_facet Shailesh Kolekar
Kristrun Gudmundsdottir
Karen Ege Olsen
Pradeesh Sivapalan
Paul Frost Clementsen
Uffe Bodtger
author_sort Shailesh Kolekar
title Adult pulmonary blastoma in an adult with urothelial cancer: A case report
title_short Adult pulmonary blastoma in an adult with urothelial cancer: A case report
title_full Adult pulmonary blastoma in an adult with urothelial cancer: A case report
title_fullStr Adult pulmonary blastoma in an adult with urothelial cancer: A case report
title_full_unstemmed Adult pulmonary blastoma in an adult with urothelial cancer: A case report
title_sort adult pulmonary blastoma in an adult with urothelial cancer: a case report
publisher Elsevier
publishDate 2021
url https://doaj.org/article/9d0d486c59a04d33bef51e935663b108
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AT karenegeolsen adultpulmonaryblastomainanadultwithurothelialcanceracasereport
AT pradeeshsivapalan adultpulmonaryblastomainanadultwithurothelialcanceracasereport
AT paulfrostclementsen adultpulmonaryblastomainanadultwithurothelialcanceracasereport
AT uffebodtger adultpulmonaryblastomainanadultwithurothelialcanceracasereport
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