Adult pulmonary blastoma in an adult with urothelial cancer: A case report
Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25–0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults.Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are...
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Elsevier
2021
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oai:doaj.org-article:9d0d486c59a04d33bef51e935663b1082021-11-12T04:32:52ZAdult pulmonary blastoma in an adult with urothelial cancer: A case report2213-007110.1016/j.rmcr.2021.101556https://doaj.org/article/9d0d486c59a04d33bef51e935663b1082021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2213007121002185https://doaj.org/toc/2213-0071Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25–0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults.Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are unclear.People with DICER1 syndrome commonly develop Pulmonary blastoma and do have concomitant or previous history of benign or malignant tumours in extra pulmonary site like kidney, thyroid, ovary cervix testicle and eye.As per our knowledge, this is the first case of adult pulmonary blastoma previously diagnosed with urothelial cancer and a strong familial predilection of malignancy, with negative genetic test for DICER1 mutations.Shailesh KolekarKristrun GudmundsdottirKaren Ege OlsenPradeesh SivapalanPaul Frost ClementsenUffe BodtgerElsevierarticlePulmonary blastomaDICER1Urothelial cancerDiseases of the respiratory systemRC705-779ENRespiratory Medicine Case Reports, Vol 34, Iss , Pp 101556- (2021) |
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Pulmonary blastoma DICER1 Urothelial cancer Diseases of the respiratory system RC705-779 |
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Pulmonary blastoma DICER1 Urothelial cancer Diseases of the respiratory system RC705-779 Shailesh Kolekar Kristrun Gudmundsdottir Karen Ege Olsen Pradeesh Sivapalan Paul Frost Clementsen Uffe Bodtger Adult pulmonary blastoma in an adult with urothelial cancer: A case report |
description |
Pulmonary blastoma is an aggressive lung cancer with incidence ranging from 0.25–0.5 of all the reported lung cancers. Although, pulmonary blastoma is seen commonly in childhood its very rare in adults.Surgical treatment is often the treatment of choice, but benefits of neoadjuvant chemotherapy are unclear.People with DICER1 syndrome commonly develop Pulmonary blastoma and do have concomitant or previous history of benign or malignant tumours in extra pulmonary site like kidney, thyroid, ovary cervix testicle and eye.As per our knowledge, this is the first case of adult pulmonary blastoma previously diagnosed with urothelial cancer and a strong familial predilection of malignancy, with negative genetic test for DICER1 mutations. |
format |
article |
author |
Shailesh Kolekar Kristrun Gudmundsdottir Karen Ege Olsen Pradeesh Sivapalan Paul Frost Clementsen Uffe Bodtger |
author_facet |
Shailesh Kolekar Kristrun Gudmundsdottir Karen Ege Olsen Pradeesh Sivapalan Paul Frost Clementsen Uffe Bodtger |
author_sort |
Shailesh Kolekar |
title |
Adult pulmonary blastoma in an adult with urothelial cancer: A case report |
title_short |
Adult pulmonary blastoma in an adult with urothelial cancer: A case report |
title_full |
Adult pulmonary blastoma in an adult with urothelial cancer: A case report |
title_fullStr |
Adult pulmonary blastoma in an adult with urothelial cancer: A case report |
title_full_unstemmed |
Adult pulmonary blastoma in an adult with urothelial cancer: A case report |
title_sort |
adult pulmonary blastoma in an adult with urothelial cancer: a case report |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/9d0d486c59a04d33bef51e935663b108 |
work_keys_str_mv |
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_version_ |
1718431305935355904 |