Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment

Lipid membrane disruption is often associated with disease but is also essential to a range of biosensing and therapeutic techniques. Here, the authors report on the development of DNA-based particles that, upon exposure to an external cue, can aggregate, disrupt lipid membranes, and arrest the moti...

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Autores principales: Michal Walczak, Ryan A. Brady, Leonardo Mancini, Claudia Contini, Roger Rubio-Sánchez, William T. Kaufhold, Pietro Cicuta, Lorenzo Di Michele
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9d121757fa9a428f9715e54ca1db4695
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spelling oai:doaj.org-article:9d121757fa9a428f9715e54ca1db46952021-12-02T17:06:12ZResponsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment10.1038/s41467-021-24989-72041-1723https://doaj.org/article/9d121757fa9a428f9715e54ca1db46952021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24989-7https://doaj.org/toc/2041-1723Lipid membrane disruption is often associated with disease but is also essential to a range of biosensing and therapeutic techniques. Here, the authors report on the development of DNA-based particles that, upon exposure to an external cue, can aggregate, disrupt lipid membranes, and arrest the motion of bacteria.Michal WalczakRyan A. BradyLeonardo ManciniClaudia ContiniRoger Rubio-SánchezWilliam T. KaufholdPietro CicutaLorenzo Di MicheleNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Michal Walczak
Ryan A. Brady
Leonardo Mancini
Claudia Contini
Roger Rubio-Sánchez
William T. Kaufhold
Pietro Cicuta
Lorenzo Di Michele
Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
description Lipid membrane disruption is often associated with disease but is also essential to a range of biosensing and therapeutic techniques. Here, the authors report on the development of DNA-based particles that, upon exposure to an external cue, can aggregate, disrupt lipid membranes, and arrest the motion of bacteria.
format article
author Michal Walczak
Ryan A. Brady
Leonardo Mancini
Claudia Contini
Roger Rubio-Sánchez
William T. Kaufhold
Pietro Cicuta
Lorenzo Di Michele
author_facet Michal Walczak
Ryan A. Brady
Leonardo Mancini
Claudia Contini
Roger Rubio-Sánchez
William T. Kaufhold
Pietro Cicuta
Lorenzo Di Michele
author_sort Michal Walczak
title Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
title_short Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
title_full Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
title_fullStr Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
title_full_unstemmed Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
title_sort responsive core-shell dna particles trigger lipid-membrane disruption and bacteria entrapment
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/9d121757fa9a428f9715e54ca1db4695
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