Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window

Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window

Stimuli-responsive nanomaterials offer the opportunity to exploit nanoscale cooperativity to improve the precision of diagnostic or therapeutic outcomes. Here, the authors report the design, synthesis and characterization of a series of degradable ultra-pH sensitive polymers that amplify small acidi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Xu Wang, Jonathan Wilhelm, Wei Li, Suxin Li, Zhaohui Wang, Gang Huang, Jian Wang, Houliang Tang, Sina Khorsandi, Zhichen Sun, Bret Evers, Jinming Gao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9d311122c77848918b4ada92cf5fbb74
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:9d311122c77848918b4ada92cf5fbb74
record_format dspace
spelling oai:doaj.org-article:9d311122c77848918b4ada92cf5fbb742021-12-02T15:37:19ZPolycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window10.1038/s41467-020-19651-72041-1723https://doaj.org/article/9d311122c77848918b4ada92cf5fbb742020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19651-7https://doaj.org/toc/2041-1723Stimuli-responsive nanomaterials offer the opportunity to exploit nanoscale cooperativity to improve the precision of diagnostic or therapeutic outcomes. Here, the authors report the design, synthesis and characterization of a series of degradable ultra-pH sensitive polymers that amplify small acidic pH changes to efficacious therapeutic outputs.Xu WangJonathan WilhelmWei LiSuxin LiZhaohui WangGang HuangJian WangHouliang TangSina KhorsandiZhichen SunBret EversJinming GaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xu Wang
Jonathan Wilhelm
Wei Li
Suxin Li
Zhaohui Wang
Gang Huang
Jian Wang
Houliang Tang
Sina Khorsandi
Zhichen Sun
Bret Evers
Jinming Gao
Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
description Stimuli-responsive nanomaterials offer the opportunity to exploit nanoscale cooperativity to improve the precision of diagnostic or therapeutic outcomes. Here, the authors report the design, synthesis and characterization of a series of degradable ultra-pH sensitive polymers that amplify small acidic pH changes to efficacious therapeutic outputs.
format article
author Xu Wang
Jonathan Wilhelm
Wei Li
Suxin Li
Zhaohui Wang
Gang Huang
Jian Wang
Houliang Tang
Sina Khorsandi
Zhichen Sun
Bret Evers
Jinming Gao
author_facet Xu Wang
Jonathan Wilhelm
Wei Li
Suxin Li
Zhaohui Wang
Gang Huang
Jian Wang
Houliang Tang
Sina Khorsandi
Zhichen Sun
Bret Evers
Jinming Gao
author_sort Xu Wang
title Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
title_short Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
title_full Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
title_fullStr Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
title_full_unstemmed Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
title_sort polycarbonate-based ultra-ph sensitive nanoparticles improve therapeutic window
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/9d311122c77848918b4ada92cf5fbb74
work_keys_str_mv AT xuwang polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT jonathanwilhelm polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT weili polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT suxinli polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT zhaohuiwang polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT ganghuang polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT jianwang polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT houliangtang polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT sinakhorsandi polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT zhichensun polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT bretevers polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
AT jinminggao polycarbonatebasedultraphsensitivenanoparticlesimprovetherapeuticwindow
_version_ 1718386248216739840

Ejemplares similares