VapC from the leptospiral VapBC toxin-antitoxin module displays ribonuclease activity on the initiator tRNA.

The prokaryotic ubiquitous Toxin-Antitoxin (TA) operons encode a stable toxin and an unstable antitoxin. The most accepted hypothesis of the physiological function of the TA system is the reversible cessation of cellular growth under stress conditions. The major TA family, VapBC is present in the sp...

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Autores principales: Alexandre P Y Lopes, Luana M Lopes, Tatiana R Fraga, Rosa M Chura-Chambi, André L Sanson, Elisabeth Cheng, Erika Nakajima, Ligia Morganti, Elizabeth A L Martins
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/9d3561fb310e4fcebb82a2243db521a2
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