MK8722, an AMPK activator, inhibiting carcinoma proliferation, invasion and migration in human pancreatic cancer cells

Background: MK8722 is a potent and systemic pan-AMPK activator. It is an effective, direct, allosteric activator of AMPK complex in many mammals. This study tried to explore the underlying anti-cancer molecular mechanism of MK8722 in human pancreatic cancer cells (PCCs). Methods: The anti-proliferat...

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Autores principales: Cheng Wang, Baojun Huang, Linxiao Sun, Xi Wang, Baofeng Zhou, Hongli Tang, Wujun Geng
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/9d4138ad7a914c57a0a12d3a87ec392e
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