Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices

Since the beginning of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus pandemic, several highly effective and safe vaccines have been produced at remarkable speed. Following global implementation of vaccination programmes, cases of thrombosis with thrombocytopenia following ad...

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Autores principales:	D. Swan, H. Enright, R. Desmond, G. Le, E. El Hassadi, B. Hennessy, F. Lynott, D. O'Keeffe, M. Crowley, L. Smyth, K. Perera, C. Jennings, F. Ni Ainle, J. Coll, K. Ryan, J. O'Donnell, M. Lavin, N. O'Connell
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Thrombosis Thrombocytopenia VITT COVID-19 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/9d50489c6c90476e8f955f3b4a822057
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spelling	oai:doaj.org-article:9d50489c6c90476e8f955f3b4a8220572021-12-04T04:36:07ZVaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices2666-572710.1016/j.tru.2021.100086https://doaj.org/article/9d50489c6c90476e8f955f3b4a8220572021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666572721000559https://doaj.org/toc/2666-5727Since the beginning of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus pandemic, several highly effective and safe vaccines have been produced at remarkable speed. Following global implementation of vaccination programmes, cases of thrombosis with thrombocytopenia following administration of adenoviral vector-based vaccines started being reported.In this review we discuss the known pathogenesis and epidemiology of so-called vaccine induced thrombocytopenia and thrombosis (VITT). We consider the available guidelines, diagnostic laboratory tests and management options for these patients. Finally, we discuss important unanswered questions and areas for future research in this novel pathoclinical entity.D. SwanH. EnrightR. DesmondG. LeE. El HassadiB. HennessyF. LynottD. O'KeeffeM. CrowleyL. SmythK. PereraC. JenningsF. Ni AinleJ. CollK. RyanJ. O'DonnellM. LavinN. O'ConnellElsevierarticleThrombosisThrombocytopeniaVITTCOVID-19Diseases of the circulatory (Cardiovascular) systemRC666-701ENThrombosis Update, Vol 5, Iss , Pp 100086- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Thrombosis Thrombocytopenia VITT COVID-19 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Thrombosis Thrombocytopenia VITT COVID-19 Diseases of the circulatory (Cardiovascular) system RC666-701 D. Swan H. Enright R. Desmond G. Le E. El Hassadi B. Hennessy F. Lynott D. O'Keeffe M. Crowley L. Smyth K. Perera C. Jennings F. Ni Ainle J. Coll K. Ryan J. O'Donnell M. Lavin N. O'Connell Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices
description	Since the beginning of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus pandemic, several highly effective and safe vaccines have been produced at remarkable speed. Following global implementation of vaccination programmes, cases of thrombosis with thrombocytopenia following administration of adenoviral vector-based vaccines started being reported.In this review we discuss the known pathogenesis and epidemiology of so-called vaccine induced thrombocytopenia and thrombosis (VITT). We consider the available guidelines, diagnostic laboratory tests and management options for these patients. Finally, we discuss important unanswered questions and areas for future research in this novel pathoclinical entity.
format	article
author	D. Swan H. Enright R. Desmond G. Le E. El Hassadi B. Hennessy F. Lynott D. O'Keeffe M. Crowley L. Smyth K. Perera C. Jennings F. Ni Ainle J. Coll K. Ryan J. O'Donnell M. Lavin N. O'Connell
author_facet	D. Swan H. Enright R. Desmond G. Le E. El Hassadi B. Hennessy F. Lynott D. O'Keeffe M. Crowley L. Smyth K. Perera C. Jennings F. Ni Ainle J. Coll K. Ryan J. O'Donnell M. Lavin N. O'Connell
author_sort	D. Swan
title	Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices
title_short	Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices
title_full	Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices
title_fullStr	Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices
title_full_unstemmed	Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices
title_sort	vaccine-induced thrombosis and thrombocytopenia (vitt) in ireland: a review of cases and current practices
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/9d50489c6c90476e8f955f3b4a822057
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Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices

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