Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs

The misuse of psychoactive substances is attracting a great deal of attention from the general public. An increase use of psychoactive substances is observed among young people who do not have enough awareness of the harmful effects of these substances. Easy access to illicit drugs at low cost and l...

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Autores principales:	Lukić Vera, Micić Ružica, Arsić Biljana, Nedović Bojan, Radosavljević Živana
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	illegal drugs cathinones phenethylamines cannabinoids tryptamines Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/9d5972e7b0d84226ae3bb924f84ffe0c
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spelling	oai:doaj.org-article:9d5972e7b0d84226ae3bb924f84ffe0c2021-12-05T14:10:44ZOverview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs2391-542010.1515/chem-2021-0196https://doaj.org/article/9d5972e7b0d84226ae3bb924f84ffe0c2021-02-01T00:00:00Zhttps://doi.org/10.1515/chem-2021-0196https://doaj.org/toc/2391-5420The misuse of psychoactive substances is attracting a great deal of attention from the general public. An increase use of psychoactive substances is observed among young people who do not have enough awareness of the harmful effects of these substances. Easy access to illicit drugs at low cost and lack of effective means of routine screening for new psychoactive substances (NPS) have contributed to the rapid increase in their use. New research and evidence suggest that drug use can cause a variety of adverse psychological and physiological effects on human health (anxiety, panic, paranoia, psychosis, and seizures). We describe different classes of these NPS drugs with emphasis on the methods used to identify them and the identification of their metabolites in biological specimens. This is the first review that thoroughly gives the literature on both natural and synthetic illegal drugs with old known data and very hot new topics and investigations, which enables the researcher to use it as a starting point in the literature exploration and planning of the own research. For the first time, the conformational analysis was done for selected illegal drugs, giving rise to the search of the biologically active conformations both theoretically and using lab experiments.Lukić VeraMicić RužicaArsić BiljanaNedović BojanRadosavljević ŽivanaDe Gruyterarticleillegal drugscathinonesphenethylaminescannabinoidstryptaminesChemistryQD1-999ENOpen Chemistry, Vol 19, Iss 1, Pp 60-106 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	illegal drugs cathinones phenethylamines cannabinoids tryptamines Chemistry QD1-999
spellingShingle	illegal drugs cathinones phenethylamines cannabinoids tryptamines Chemistry QD1-999 Lukić Vera Micić Ružica Arsić Biljana Nedović Bojan Radosavljević Živana Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
description	The misuse of psychoactive substances is attracting a great deal of attention from the general public. An increase use of psychoactive substances is observed among young people who do not have enough awareness of the harmful effects of these substances. Easy access to illicit drugs at low cost and lack of effective means of routine screening for new psychoactive substances (NPS) have contributed to the rapid increase in their use. New research and evidence suggest that drug use can cause a variety of adverse psychological and physiological effects on human health (anxiety, panic, paranoia, psychosis, and seizures). We describe different classes of these NPS drugs with emphasis on the methods used to identify them and the identification of their metabolites in biological specimens. This is the first review that thoroughly gives the literature on both natural and synthetic illegal drugs with old known data and very hot new topics and investigations, which enables the researcher to use it as a starting point in the literature exploration and planning of the own research. For the first time, the conformational analysis was done for selected illegal drugs, giving rise to the search of the biologically active conformations both theoretically and using lab experiments.
format	article
author	Lukić Vera Micić Ružica Arsić Biljana Nedović Bojan Radosavljević Živana
author_facet	Lukić Vera Micić Ružica Arsić Biljana Nedović Bojan Radosavljević Živana
author_sort	Lukić Vera
title	Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
title_short	Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
title_full	Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
title_fullStr	Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
title_full_unstemmed	Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
title_sort	overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/9d5972e7b0d84226ae3bb924f84ffe0c
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Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs

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