Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy

Revascularization of both left main and bifurcation lesions is currently considered an important feature of complex percutaneous coronary intervention (PCI), whereas stenting distal left main bifurcation is fairly challenging. Recent evidence shows that such lesions are associated with an increased...

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Autores principales:	Charalampos Varlamos, Ioannis Lianos, Despoina-Rafailia Benetou, Dimitrios Alexopoulos
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2021
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/9d5b5473bb8c423f83308d30bd397e07
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spelling	oai:doaj.org-article:9d5b5473bb8c423f83308d30bd397e072021-12-04T16:04:37ZLeft Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy10.15420/usc.2020.341758-390X1758-3896https://doaj.org/article/9d5b5473bb8c423f83308d30bd397e072021-06-01T00:00:00Zhttps://uscjournal.com/articleindex/usc.2020.34https://doaj.org/toc/1758-3896https://doaj.org/toc/1758-390XRevascularization of both left main and bifurcation lesions is currently considered an important feature of complex percutaneous coronary intervention (PCI), whereas stenting distal left main bifurcation is fairly challenging. Recent evidence shows that such lesions are associated with an increased risk of ischemic events. There is no universal consensus on the optimal PCI strategy or the appropriate type and duration of antithrombotic therapy to mitigate the thrombotic risk. Prolonged dual antiplatelet therapy or use of more potent P2Y12 inhibitors have been investigated in the context of this high-risk subset of the population undergoing PCI. Thus, while complex PCI is a growing field in interventional cardiology, left main and bifurcation PCI constitutes a fair amount of the total complex procedures performed recently, and there is cumulative interest regarding antithrombotic therapy type and duration in this subset of patients, with decision-making mostly based on clinical presentation, baseline bleeding, and ischemic risk, as well as the performed stenting strategy.Charalampos VarlamosIoannis LianosDespoina-Rafailia BenetouDimitrios AlexopoulosRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENUS Cardiology Review , Vol 15, Iss , Pp - (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Charalampos Varlamos Ioannis Lianos Despoina-Rafailia Benetou Dimitrios Alexopoulos Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy
description	Revascularization of both left main and bifurcation lesions is currently considered an important feature of complex percutaneous coronary intervention (PCI), whereas stenting distal left main bifurcation is fairly challenging. Recent evidence shows that such lesions are associated with an increased risk of ischemic events. There is no universal consensus on the optimal PCI strategy or the appropriate type and duration of antithrombotic therapy to mitigate the thrombotic risk. Prolonged dual antiplatelet therapy or use of more potent P2Y12 inhibitors have been investigated in the context of this high-risk subset of the population undergoing PCI. Thus, while complex PCI is a growing field in interventional cardiology, left main and bifurcation PCI constitutes a fair amount of the total complex procedures performed recently, and there is cumulative interest regarding antithrombotic therapy type and duration in this subset of patients, with decision-making mostly based on clinical presentation, baseline bleeding, and ischemic risk, as well as the performed stenting strategy.
format	article
author	Charalampos Varlamos Ioannis Lianos Despoina-Rafailia Benetou Dimitrios Alexopoulos
author_facet	Charalampos Varlamos Ioannis Lianos Despoina-Rafailia Benetou Dimitrios Alexopoulos
author_sort	Charalampos Varlamos
title	Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy
title_short	Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy
title_full	Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy
title_fullStr	Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy
title_full_unstemmed	Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy
title_sort	left main disease and bifurcation percutaneous coronary intervention: focus on antithrombotic therapy
publisher	Radcliffe Medical Media
publishDate	2021
url	https://doaj.org/article/9d5b5473bb8c423f83308d30bd397e07
work_keys_str_mv	AT charalamposvarlamos leftmaindiseaseandbifurcationpercutaneouscoronaryinterventionfocusonantithrombotictherapy AT ioannislianos leftmaindiseaseandbifurcationpercutaneouscoronaryinterventionfocusonantithrombotictherapy AT despoinarafailiabenetou leftmaindiseaseandbifurcationpercutaneouscoronaryinterventionfocusonantithrombotictherapy AT dimitriosalexopoulos leftmaindiseaseandbifurcationpercutaneouscoronaryinterventionfocusonantithrombotictherapy
_version_	1718372689807147008

Left Main Disease and Bifurcation Percutaneous Coronary Intervention: Focus on Antithrombotic Therapy

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