Genetic framework of type 2 diabetes mellitus

More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.

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Auteurs principaux:	Irina Arkad'evna Bondar', Olesya Yur'evna Shabel'nikova
Format:	article
Langue:	EN RU
Publié:	Endocrinology Research Centre 2013
Sujets:	type 2 diabetes mellitus genetics beta-cell dysfunction insulin resistance Nutritional diseases. Deficiency diseases RC620-627
Accès en ligne:	https://doaj.org/article/9d5d5da8687a41c0a2fabd1e00a23ebe
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spelling	oai:doaj.org-article:9d5d5da8687a41c0a2fabd1e00a23ebe2021-11-14T09:00:18ZGenetic framework of type 2 diabetes mellitus2072-03512072-037810.14341/DM2013411-16https://doaj.org/article/9d5d5da8687a41c0a2fabd1e00a23ebe2013-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/3847https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.Irina Arkad'evna Bondar'Olesya Yur'evna Shabel'nikovaEndocrinology Research Centrearticletype 2 diabetes mellitusgeneticsbeta-cell dysfunctioninsulin resistanceNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 4, Pp 11-16 (2013)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 2 diabetes mellitus genetics beta-cell dysfunction insulin resistance Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 2 diabetes mellitus genetics beta-cell dysfunction insulin resistance Nutritional diseases. Deficiency diseases RC620-627 Irina Arkad'evna Bondar' Olesya Yur'evna Shabel'nikova Genetic framework of type 2 diabetes mellitus
description	More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.
format	article
author	Irina Arkad'evna Bondar' Olesya Yur'evna Shabel'nikova
author_facet	Irina Arkad'evna Bondar' Olesya Yur'evna Shabel'nikova
author_sort	Irina Arkad'evna Bondar'
title	Genetic framework of type 2 diabetes mellitus
title_short	Genetic framework of type 2 diabetes mellitus
title_full	Genetic framework of type 2 diabetes mellitus
title_fullStr	Genetic framework of type 2 diabetes mellitus
title_full_unstemmed	Genetic framework of type 2 diabetes mellitus
title_sort	genetic framework of type 2 diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2013
url	https://doaj.org/article/9d5d5da8687a41c0a2fabd1e00a23ebe
work_keys_str_mv	AT irinaarkadevnabondar geneticframeworkoftype2diabetesmellitus AT olesyayurevnashabelnikova geneticframeworkoftype2diabetesmellitus
_version_	1718429598161567744

Genetic framework of type 2 diabetes mellitus

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