Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact.
Acute myeloid leukaemia (AML) is characterised by phenotypic heterogeneity, which we hypothesise is a consequence of deregulated differentiation with transcriptional reminiscence of the normal compartment or cell-of-origin. Here, we propose a classification system based on normal myeloid progenitor...
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Auteurs principaux: | Anna A Schönherz, Julie Støve Bødker, Alexander Schmitz, Rasmus Froberg Brøndum, Lasse Hjort Jakobsen, Anne Stidsholt Roug, Marianne T Severinsen, Tarec C El-Galaly, Paw Jensen, Hans Erik Johnsen, Martin Bøgsted, Karen Dybkær |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2020
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Accès en ligne: | https://doaj.org/article/9d6f994c235e49a98003993006237fd0 |
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