Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit

BACKGROUND AND OBJECTIVE: Consumption of high fat meal causes a sudden increase in blood lipids, oxidative stress and endothelial dysfunction. Sumac has antioxidant activity and this study was aimed to determine the effect of sumac consumption on some atherosclerosis risk factors due to high fat foo...

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Autores principales:	M Setorki, M Rafieian, E Heidarian, K Ghatreh, N , Shahinfard, R Ansari, Z Forouzandeh
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2012
Materias:	atherosclerosis traditional medicine lipid metabolism Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9d790aa872894d05b64ab3f56b494dac
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spelling	oai:doaj.org-article:9d790aa872894d05b64ab3f56b494dac2021-11-10T08:53:11ZEffect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit1561-41072251-7170https://doaj.org/article/9d790aa872894d05b64ab3f56b494dac2012-05-01T00:00:00Zhttp://jbums.org/article-1-4088-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Consumption of high fat meal causes a sudden increase in blood lipids, oxidative stress and endothelial dysfunction. Sumac has antioxidant activity and this study was aimed to determine the effect of sumac consumption on some atherosclerosis risk factors due to high fat food stress in rabbits.METHODS: In an experimental study, 24 male New Zealand rabbits were randomly designated into three groups: normal diet group, a diet containing 1% cholesterol, a diet containing 1% cholesterol with 2% Sumac powder. Oxidative stress and atherosclerosis risk factors, including glucose, total cholesterol (TC), triglyceride (TG), apolipoprotein B (ApoB), low density lipoprotein (LDL), nitrite, nitrate, fibrinogen, factor VII, liver transaminases (ALT and AST) were measured before the experiment and 3 hours after feeding.FINDINGS: High cholesterol food (1%) increased TC, fibrinogen, TG, glucose, nitrate, LDL-C, ALT and AST (p<0.05). Consumption of sumac caused a significant decrease in glucose (30.15%), LDL-C (58.17%), TC (29.5%), ALT (20.55%), AST (17.46%) and fibrinogen (17.92%) compared to hypercholesterolemic diet group (p<0.05). No significant difference was found between sumac group and hypercholesterolemic diet group in triglyceride (TG), factor VII, nitrite, nitrate and ApoB.CONCLUSION: The results of this study showed that acute consumption of sumac might have a protective effect on some of risk factors of atherosclerosis, oxidative stress and liver enzymes, due to high fat food stress.M SetorkiM RafieianE HeidarianK GhatrehN , ShahinfardR AnsariZ ForouzandehBabol University of Medical Sciencesarticleatherosclerosistraditional medicinelipid metabolismMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 14, Iss 3, Pp 38-45 (2012)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	atherosclerosis traditional medicine lipid metabolism Medicine R Medicine (General) R5-920
spellingShingle	atherosclerosis traditional medicine lipid metabolism Medicine R Medicine (General) R5-920 M Setorki M Rafieian E Heidarian K Ghatreh N , Shahinfard R Ansari Z Forouzandeh Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit
description	BACKGROUND AND OBJECTIVE: Consumption of high fat meal causes a sudden increase in blood lipids, oxidative stress and endothelial dysfunction. Sumac has antioxidant activity and this study was aimed to determine the effect of sumac consumption on some atherosclerosis risk factors due to high fat food stress in rabbits.METHODS: In an experimental study, 24 male New Zealand rabbits were randomly designated into three groups: normal diet group, a diet containing 1% cholesterol, a diet containing 1% cholesterol with 2% Sumac powder. Oxidative stress and atherosclerosis risk factors, including glucose, total cholesterol (TC), triglyceride (TG), apolipoprotein B (ApoB), low density lipoprotein (LDL), nitrite, nitrate, fibrinogen, factor VII, liver transaminases (ALT and AST) were measured before the experiment and 3 hours after feeding.FINDINGS: High cholesterol food (1%) increased TC, fibrinogen, TG, glucose, nitrate, LDL-C, ALT and AST (p<0.05). Consumption of sumac caused a significant decrease in glucose (30.15%), LDL-C (58.17%), TC (29.5%), ALT (20.55%), AST (17.46%) and fibrinogen (17.92%) compared to hypercholesterolemic diet group (p<0.05). No significant difference was found between sumac group and hypercholesterolemic diet group in triglyceride (TG), factor VII, nitrite, nitrate and ApoB.CONCLUSION: The results of this study showed that acute consumption of sumac might have a protective effect on some of risk factors of atherosclerosis, oxidative stress and liver enzymes, due to high fat food stress.
format	article
author	M Setorki M Rafieian E Heidarian K Ghatreh N , Shahinfard R Ansari Z Forouzandeh
author_facet	M Setorki M Rafieian E Heidarian K Ghatreh N , Shahinfard R Ansari Z Forouzandeh
author_sort	M Setorki
title	Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit
title_short	Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit
title_full	Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit
title_fullStr	Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit
title_full_unstemmed	Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit
title_sort	effect of rhus coriaria consumption with high cholesterol food on some atherosclerosis risk factors in rabbit
publisher	Babol University of Medical Sciences
publishDate	2012
url	https://doaj.org/article/9d790aa872894d05b64ab3f56b494dac
work_keys_str_mv	AT msetorki effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit AT mrafieian effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit AT eheidarian effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit AT kghatreh effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit AT nshahinfard effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit AT ransari effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit AT zforouzandeh effectofrhuscoriariaconsumptionwithhighcholesterolfoodonsomeatherosclerosisriskfactorsinrabbit
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Effect of Rhus Coriaria Consumption with High Cholesterol Food on Some Atherosclerosis Risk Factors in Rabbit

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