Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.

Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.

Mostrar otras versiones (1)

<h4>Background</h4>Handgrip strength (HGS) is an alternative tool to evaluate respiratory muscle function. HGS cutoff value indicating extubation success or failure has not been investigated. This study aimed to determine HGS cutoff value to predict successful extubation.<h4>Method...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Narongkorn Saiphoklang, Nattawadee Mokkongphai
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/9d80484009b04231810362e8cb1bf204
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:9d80484009b04231810362e8cb1bf204
record_format dspace
spelling oai:doaj.org-article:9d80484009b04231810362e8cb1bf2042021-12-02T20:16:38ZHandgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.1932-620310.1371/journal.pone.0258971https://doaj.org/article/9d80484009b04231810362e8cb1bf2042021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0258971https://doaj.org/toc/1932-6203<h4>Background</h4>Handgrip strength (HGS) is an alternative tool to evaluate respiratory muscle function. HGS cutoff value indicating extubation success or failure has not been investigated. This study aimed to determine HGS cutoff value to predict successful extubation.<h4>Methods</h4>A prospective study was conducted. Patients requiring intubated mechanical ventilation with intubation ≥ 48 hours in medical wards were recruited. HGS test was performed at 10 minutes before and 30 minutes after spontaneous breathing trial (SBT). Rapid shallow breathing index (RSBI) was measured at 10 minutes before SBT.<h4>Results</h4>Ninety-three patients (58% men) were included. Mean age was 71.6 ± 15.2 years. Weaning failure rate was 6.5%. The area under the ROC curve of 0.84 for the best HGS cutoff value at 10 minutes before SBT was 12.7 kg, with 75.9% sensitivity and 83.3% specificity (P = 0.005). The best HSG cutoff value at 30 minutes after SBT was 14.9 kg, with the area under the ROC curve of 0.82, with 58.6% sensitivity and 83.3% specificity (P = 0.009). The best RSBI cutoff value was 43.5 breaths/min/L, with the area under the ROC curve of 0.46, 33.3% sensitivity and 66.6% specificity (P = 0.737).<h4>Conclusions</h4>HGS may be a predictive tool to guide extubation with better sensitivity and specificity than RSBI. A prospective study is needed to verify HGS test as adjunctive to RSBI in ventilator weaning protocol.Narongkorn SaiphoklangNattawadee MokkongphaiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0258971 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Narongkorn Saiphoklang
Nattawadee Mokkongphai
Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
description <h4>Background</h4>Handgrip strength (HGS) is an alternative tool to evaluate respiratory muscle function. HGS cutoff value indicating extubation success or failure has not been investigated. This study aimed to determine HGS cutoff value to predict successful extubation.<h4>Methods</h4>A prospective study was conducted. Patients requiring intubated mechanical ventilation with intubation ≥ 48 hours in medical wards were recruited. HGS test was performed at 10 minutes before and 30 minutes after spontaneous breathing trial (SBT). Rapid shallow breathing index (RSBI) was measured at 10 minutes before SBT.<h4>Results</h4>Ninety-three patients (58% men) were included. Mean age was 71.6 ± 15.2 years. Weaning failure rate was 6.5%. The area under the ROC curve of 0.84 for the best HGS cutoff value at 10 minutes before SBT was 12.7 kg, with 75.9% sensitivity and 83.3% specificity (P = 0.005). The best HSG cutoff value at 30 minutes after SBT was 14.9 kg, with the area under the ROC curve of 0.82, with 58.6% sensitivity and 83.3% specificity (P = 0.009). The best RSBI cutoff value was 43.5 breaths/min/L, with the area under the ROC curve of 0.46, 33.3% sensitivity and 66.6% specificity (P = 0.737).<h4>Conclusions</h4>HGS may be a predictive tool to guide extubation with better sensitivity and specificity than RSBI. A prospective study is needed to verify HGS test as adjunctive to RSBI in ventilator weaning protocol.
format article
author Narongkorn Saiphoklang
Nattawadee Mokkongphai
author_facet Narongkorn Saiphoklang
Nattawadee Mokkongphai
author_sort Narongkorn Saiphoklang
title Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
title_short Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
title_full Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
title_fullStr Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
title_full_unstemmed Handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
title_sort handgrip strength cutoff value predicting successful extubation in mechanically ventilated patients.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/9d80484009b04231810362e8cb1bf204
work_keys_str_mv AT narongkornsaiphoklang handgripstrengthcutoffvaluepredictingsuccessfulextubationinmechanicallyventilatedpatients
AT nattawadeemokkongphai handgripstrengthcutoffvaluepredictingsuccessfulextubationinmechanicallyventilatedpatients
_version_ 1718374483976257536

Ejemplares similares