Translocation of Dense Granule Effectors across the Parasitophorous Vacuole Membrane in <italic toggle="yes">Toxoplasma-</italic>Infected Cells Requires the Activity of ROP17, a Rhoptry Protein Kinase

Translocation of Dense Granule Effectors across the Parasitophorous Vacuole Membrane in <italic toggle="yes">Toxoplasma-</italic>Infected Cells Requires the Activity of ROP17, a Rhoptry Protein Kinase

ABSTRACT Toxoplasma gondii tachyzoites co-opt host cell functions through introduction of a large set of rhoptry- and dense granule-derived effector proteins. These effectors reach the host cytosol through different means: direct injection for rhoptry effectors and translocation across the parasitop...

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Autores principales: Michael W. Panas, Abel Ferrel, Adit Naor, Elizabeth Tenborg, Hernan A. Lorenzi, John C. Boothroyd
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Toxoplasma gondii
effector proteins
host-parasite relationship
kinases
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/9d8fdf4a8eaa474880523088ef5e0042
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