Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues

Current available tissue clearing techniques are mostly used for rodent tissues. Here, the authors develop OPTIClear solution for fresh and archival human brain tissue clearing and establish associated protocols for three-dimensional histological investigations.

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Autores principales:	Hei Ming Lai, Alan King Lun Liu, Harry Ho Man Ng, Marc H. Goldfinger, Tsz Wing Chau, John DeFelice, Bension S. Tilley, Wai Man Wong, Wutian Wu, Steve M. Gentleman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9d9228a4c7a24d749448e9d69657ba3c
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spelling	oai:doaj.org-article:9d9228a4c7a24d749448e9d69657ba3c2021-12-02T17:31:14ZNext generation histology methods for three-dimensional imaging of fresh and archival human brain tissues10.1038/s41467-018-03359-w2041-1723https://doaj.org/article/9d9228a4c7a24d749448e9d69657ba3c2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03359-whttps://doaj.org/toc/2041-1723Current available tissue clearing techniques are mostly used for rodent tissues. Here, the authors develop OPTIClear solution for fresh and archival human brain tissue clearing and establish associated protocols for three-dimensional histological investigations.Hei Ming LaiAlan King Lun LiuHarry Ho Man NgMarc H. GoldfingerTsz Wing ChauJohn DeFeliceBension S. TilleyWai Man WongWutian WuSteve M. GentlemanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hei Ming Lai Alan King Lun Liu Harry Ho Man Ng Marc H. Goldfinger Tsz Wing Chau John DeFelice Bension S. Tilley Wai Man Wong Wutian Wu Steve M. Gentleman Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
description	Current available tissue clearing techniques are mostly used for rodent tissues. Here, the authors develop OPTIClear solution for fresh and archival human brain tissue clearing and establish associated protocols for three-dimensional histological investigations.
format	article
author	Hei Ming Lai Alan King Lun Liu Harry Ho Man Ng Marc H. Goldfinger Tsz Wing Chau John DeFelice Bension S. Tilley Wai Man Wong Wutian Wu Steve M. Gentleman
author_facet	Hei Ming Lai Alan King Lun Liu Harry Ho Man Ng Marc H. Goldfinger Tsz Wing Chau John DeFelice Bension S. Tilley Wai Man Wong Wutian Wu Steve M. Gentleman
author_sort	Hei Ming Lai
title	Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
title_short	Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
title_full	Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
title_fullStr	Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
title_full_unstemmed	Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
title_sort	next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9d9228a4c7a24d749448e9d69657ba3c
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Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues

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