Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase

The number of corneal surgeries steadily grew in recent years and boosted the development of corneal biomechanical models. These models can contribute to simulating surgery by reducing associated risks and the need for secondary interventions due to ectasias or other problems related to correcting o...

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Autores principales:	Carmelo Gómez, David P. Piñero, Manuel Paredes, Jorge L. Alió, Francisco Cavas
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	finite element biomechanical stability reverse modelling patient-specific geometric tomographer CAD Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/9d95362b500743c6a1d6beff4cdb5f6a
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spelling	oai:doaj.org-article:9d95362b500743c6a1d6beff4cdb5f6a2021-11-25T16:38:41ZIterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase10.3390/app1122108192076-3417https://doaj.org/article/9d95362b500743c6a1d6beff4cdb5f6a2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/10819https://doaj.org/toc/2076-3417The number of corneal surgeries steadily grew in recent years and boosted the development of corneal biomechanical models. These models can contribute to simulating surgery by reducing associated risks and the need for secondary interventions due to ectasias or other problems related to correcting other diseases. Biomechanical models are based on the geometry obtained with corneal topography, which is affected by intraocular pressure and material properties. Knowledge of stress distribution in the measurement phase is a key factor for improving the accuracy of in silico mechanical models. In this work, the results obtained by two different methods: prestress method and displacements method were compared to evaluate the stress and strain distribution in a general geometric model based on the Navarro eye geometry and two real corneal geometries. The results show that both methods are equivalent for the achievement of the stress distribution in the measurement phase. Stress distribution over the corneal geometry in the measurement phase is a key factor for accurate biomechanical simulations, and these simulations could help to develop patient-specific models and reduce the number of secondary interventions in clinical practice.Carmelo GómezDavid P. PiñeroManuel ParedesJorge L. AlióFrancisco CavasMDPI AGarticlefinite elementbiomechanical stabilityreverse modellingpatient-specific geometrictomographerCADTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10819, p 10819 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	finite element biomechanical stability reverse modelling patient-specific geometric tomographer CAD Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
spellingShingle	finite element biomechanical stability reverse modelling patient-specific geometric tomographer CAD Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 Carmelo Gómez David P. Piñero Manuel Paredes Jorge L. Alió Francisco Cavas Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase
description	The number of corneal surgeries steadily grew in recent years and boosted the development of corneal biomechanical models. These models can contribute to simulating surgery by reducing associated risks and the need for secondary interventions due to ectasias or other problems related to correcting other diseases. Biomechanical models are based on the geometry obtained with corneal topography, which is affected by intraocular pressure and material properties. Knowledge of stress distribution in the measurement phase is a key factor for improving the accuracy of in silico mechanical models. In this work, the results obtained by two different methods: prestress method and displacements method were compared to evaluate the stress and strain distribution in a general geometric model based on the Navarro eye geometry and two real corneal geometries. The results show that both methods are equivalent for the achievement of the stress distribution in the measurement phase. Stress distribution over the corneal geometry in the measurement phase is a key factor for accurate biomechanical simulations, and these simulations could help to develop patient-specific models and reduce the number of secondary interventions in clinical practice.
format	article
author	Carmelo Gómez David P. Piñero Manuel Paredes Jorge L. Alió Francisco Cavas
author_facet	Carmelo Gómez David P. Piñero Manuel Paredes Jorge L. Alió Francisco Cavas
author_sort	Carmelo Gómez
title	Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase
title_short	Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase
title_full	Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase
title_fullStr	Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase
title_full_unstemmed	Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase
title_sort	iterative methods for the biomechanical evaluation of corneal response. a case study in the measurement phase
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9d95362b500743c6a1d6beff4cdb5f6a
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Iterative Methods for the Biomechanical Evaluation of Corneal Response. A Case Study in the Measurement Phase

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