SARS-CoV-2 infection and transmission in the North American deer mouse

Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness. Additionally, infected deer mice can transmit...

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Autores principales: Bryan D. Griffin, Mable Chan, Nikesh Tailor, Emelissa J. Mendoza, Anders Leung, Bryce M. Warner, Ana T. Duggan, Estella Moffat, Shihua He, Lauren Garnett, Kaylie N. Tran, Logan Banadyga, Alixandra Albietz, Kevin Tierney, Jonathan Audet, Alexander Bello, Robert Vendramelli, Amrit S. Boese, Lisa Fernando, L. Robbin Lindsay, Claire M. Jardine, Heidi Wood, Guillaume Poliquin, James E. Strong, Michael Drebot, David Safronetz, Carissa Embury-Hyatt, Darwyn Kobasa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9da1c4d9e45e4f76a8779fa6d68d2b3b
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spelling oai:doaj.org-article:9da1c4d9e45e4f76a8779fa6d68d2b3b2021-12-02T17:39:48ZSARS-CoV-2 infection and transmission in the North American deer mouse10.1038/s41467-021-23848-92041-1723https://doaj.org/article/9da1c4d9e45e4f76a8779fa6d68d2b3b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23848-9https://doaj.org/toc/2041-1723Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness. Additionally, infected deer mice can transmit SARS-CoV-2 to naïve deer mice.Bryan D. GriffinMable ChanNikesh TailorEmelissa J. MendozaAnders LeungBryce M. WarnerAna T. DugganEstella MoffatShihua HeLauren GarnettKaylie N. TranLogan BanadygaAlixandra AlbietzKevin TierneyJonathan AudetAlexander BelloRobert VendramelliAmrit S. BoeseLisa FernandoL. Robbin LindsayClaire M. JardineHeidi WoodGuillaume PoliquinJames E. StrongMichael DrebotDavid SafronetzCarissa Embury-HyattDarwyn KobasaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bryan D. Griffin
Mable Chan
Nikesh Tailor
Emelissa J. Mendoza
Anders Leung
Bryce M. Warner
Ana T. Duggan
Estella Moffat
Shihua He
Lauren Garnett
Kaylie N. Tran
Logan Banadyga
Alixandra Albietz
Kevin Tierney
Jonathan Audet
Alexander Bello
Robert Vendramelli
Amrit S. Boese
Lisa Fernando
L. Robbin Lindsay
Claire M. Jardine
Heidi Wood
Guillaume Poliquin
James E. Strong
Michael Drebot
David Safronetz
Carissa Embury-Hyatt
Darwyn Kobasa
SARS-CoV-2 infection and transmission in the North American deer mouse
description Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness. Additionally, infected deer mice can transmit SARS-CoV-2 to naïve deer mice.
format article
author Bryan D. Griffin
Mable Chan
Nikesh Tailor
Emelissa J. Mendoza
Anders Leung
Bryce M. Warner
Ana T. Duggan
Estella Moffat
Shihua He
Lauren Garnett
Kaylie N. Tran
Logan Banadyga
Alixandra Albietz
Kevin Tierney
Jonathan Audet
Alexander Bello
Robert Vendramelli
Amrit S. Boese
Lisa Fernando
L. Robbin Lindsay
Claire M. Jardine
Heidi Wood
Guillaume Poliquin
James E. Strong
Michael Drebot
David Safronetz
Carissa Embury-Hyatt
Darwyn Kobasa
author_facet Bryan D. Griffin
Mable Chan
Nikesh Tailor
Emelissa J. Mendoza
Anders Leung
Bryce M. Warner
Ana T. Duggan
Estella Moffat
Shihua He
Lauren Garnett
Kaylie N. Tran
Logan Banadyga
Alixandra Albietz
Kevin Tierney
Jonathan Audet
Alexander Bello
Robert Vendramelli
Amrit S. Boese
Lisa Fernando
L. Robbin Lindsay
Claire M. Jardine
Heidi Wood
Guillaume Poliquin
James E. Strong
Michael Drebot
David Safronetz
Carissa Embury-Hyatt
Darwyn Kobasa
author_sort Bryan D. Griffin
title SARS-CoV-2 infection and transmission in the North American deer mouse
title_short SARS-CoV-2 infection and transmission in the North American deer mouse
title_full SARS-CoV-2 infection and transmission in the North American deer mouse
title_fullStr SARS-CoV-2 infection and transmission in the North American deer mouse
title_full_unstemmed SARS-CoV-2 infection and transmission in the North American deer mouse
title_sort sars-cov-2 infection and transmission in the north american deer mouse
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/9da1c4d9e45e4f76a8779fa6d68d2b3b
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