Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus
Aims. Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. Materials and methods. 140 patients (63 of them were also diabetic) re...
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Endocrinology Research Centre
2012
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oai:doaj.org-article:9da962cc12024b6d9cf14ec7c8fa84322021-11-14T09:00:17ZPrognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus2072-03512072-037810.14341/2072-0351-5536https://doaj.org/article/9da962cc12024b6d9cf14ec7c8fa84322012-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5536https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aims. Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. Materials and methods. 140 patients (63 of them were also diabetic) received follow-up for cardiovascular events during12 months after an episode of unstable angina pectoris. Upon hospitalization for acute coronary syndrome analyses wereperformed to assess the degree of systemic inflammation evaluating plasma concentration of pro- and anti-inflammatorymarkers (CRP, fibrinogen, IL-6, -8, -10, TNF-?), as well as blood glucose and glycated haemoglobin HbA1c. Results. TNF-? and IL-6 levels were significantly higher in patients with unfavorable prognosis (pOlga Leonidovna BarbarashAleksey Nikolaevich SuminOlesya Evgen'evna AvramenkoAnastasia Vyacheslavovna OsokinaAleksey Vladimirovich VeremeevEndocrinology Research Centrearticleunstable anginanon-specific inflammationunfavorable prognosisdiabetes mellitusNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 15, Iss 4, Pp 39-45 (2012) |
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EN RU |
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unstable angina non-specific inflammation unfavorable prognosis diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627 |
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unstable angina non-specific inflammation unfavorable prognosis diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627 Olga Leonidovna Barbarash Aleksey Nikolaevich Sumin Olesya Evgen'evna Avramenko Anastasia Vyacheslavovna Osokina Aleksey Vladimirovich Veremeev Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| description |
Aims. Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. Materials and methods. 140 patients (63 of them were also diabetic) received follow-up for cardiovascular events during12 months after an episode of unstable angina pectoris. Upon hospitalization for acute coronary syndrome analyses wereperformed to assess the degree of systemic inflammation evaluating plasma concentration of pro- and anti-inflammatorymarkers (CRP, fibrinogen, IL-6, -8, -10, TNF-?), as well as blood glucose and glycated haemoglobin HbA1c. Results. TNF-? and IL-6 levels were significantly higher in patients with unfavorable prognosis (p |
| format |
article |
| author |
Olga Leonidovna Barbarash Aleksey Nikolaevich Sumin Olesya Evgen'evna Avramenko Anastasia Vyacheslavovna Osokina Aleksey Vladimirovich Veremeev |
| author_facet |
Olga Leonidovna Barbarash Aleksey Nikolaevich Sumin Olesya Evgen'evna Avramenko Anastasia Vyacheslavovna Osokina Aleksey Vladimirovich Veremeev |
| author_sort |
Olga Leonidovna Barbarash |
| title |
Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_short |
Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_full |
Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_fullStr |
Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_full_unstemmed |
Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_sort |
prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| publisher |
Endocrinology Research Centre |
| publishDate |
2012 |
| url |
https://doaj.org/article/9da962cc12024b6d9cf14ec7c8fa8432 |
| work_keys_str_mv |
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