Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease

Liucan Wang, Min Yu, Hua Yang Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Min Yu; Hua Yang Tel/Fax +8623-687-55705Email yumimianbao@163.com; huayang@tmmu.edu.cnAbstract: The effective colon drug delivery rem...

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Autores principales:	Wang L, Yu M, Yang H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	inflammatory bowel disease gastrointestinal tract microenvironment drug delivery syatems precise therapy diagnose Pathology RB1-214 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/9dbd1fd62351448e91b339f437c02723
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spelling	oai:doaj.org-article:9dbd1fd62351448e91b339f437c027232021-12-02T15:29:03ZRecent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease1178-7031https://doaj.org/article/9dbd1fd62351448e91b339f437c027232021-04-01T00:00:00Zhttps://www.dovepress.com/recent-progress-in-the-diagnosis-and-precise-nanocarrier-mediated-ther-peer-reviewed-fulltext-article-JIRhttps://doaj.org/toc/1178-7031Liucan Wang, Min Yu, Hua Yang Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Min Yu; Hua Yang Tel/Fax +8623-687-55705Email yumimianbao@163.com; huayang@tmmu.edu.cnAbstract: The effective colon drug delivery remains to be an international frontier research in inflammatory bowel disease (IBD) therapy. The exploration and research of nanocarrier-based nanomedicine with great potential brings new opportunities for IBD therapy and diagnoses. Functional nanocarriers with varying morphology and characteristics can not only effectively avoid the destruction of the complex gastrointestinal (GI) tract microenvironment but also endow drugs with target therapy and improved bioavailability, thus elevating therapeutic efﬁcacy. In this review, we illustrated several challenges in IBD therapy, then emphasis on some latest research progress of nanoparticles based therapy of oral administration, rectal administration and parenteral administration, as well as IBD diagnoses. Finally, we described the future perspective of nanocarriers in the treatment and diagnoses of IBD.Keywords: inflammatory bowel disease, gastrointestinal tract microenvironment, drug delivery system, precise therapy, diagnoseWang LYu MYang HDove Medical Pressarticleinflammatory bowel diseasegastrointestinal tract microenvironmentdrug delivery syatemsprecise therapydiagnosePathologyRB1-214Therapeutics. PharmacologyRM1-950ENJournal of Inflammation Research, Vol Volume 14, Pp 1701-1716 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	inflammatory bowel disease gastrointestinal tract microenvironment drug delivery syatems precise therapy diagnose Pathology RB1-214 Therapeutics. Pharmacology RM1-950
spellingShingle	inflammatory bowel disease gastrointestinal tract microenvironment drug delivery syatems precise therapy diagnose Pathology RB1-214 Therapeutics. Pharmacology RM1-950 Wang L Yu M Yang H Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease
description	Liucan Wang, Min Yu, Hua Yang Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Min Yu; Hua Yang Tel/Fax +8623-687-55705Email yumimianbao@163.com; huayang@tmmu.edu.cnAbstract: The effective colon drug delivery remains to be an international frontier research in inflammatory bowel disease (IBD) therapy. The exploration and research of nanocarrier-based nanomedicine with great potential brings new opportunities for IBD therapy and diagnoses. Functional nanocarriers with varying morphology and characteristics can not only effectively avoid the destruction of the complex gastrointestinal (GI) tract microenvironment but also endow drugs with target therapy and improved bioavailability, thus elevating therapeutic efﬁcacy. In this review, we illustrated several challenges in IBD therapy, then emphasis on some latest research progress of nanoparticles based therapy of oral administration, rectal administration and parenteral administration, as well as IBD diagnoses. Finally, we described the future perspective of nanocarriers in the treatment and diagnoses of IBD.Keywords: inflammatory bowel disease, gastrointestinal tract microenvironment, drug delivery system, precise therapy, diagnose
format	article
author	Wang L Yu M Yang H
author_facet	Wang L Yu M Yang H
author_sort	Wang L
title	Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease
title_short	Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease
title_full	Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease
title_fullStr	Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease
title_full_unstemmed	Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease
title_sort	recent progress in the diagnosis and precise nanocarrier-mediated therapy of inflammatory bowel disease
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/9dbd1fd62351448e91b339f437c02723
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Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease

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