Single-molecule detection on a portable 3D-printed microscope

Single-molecule in vitro assays require dedicated confocal microscopes equipped with fluorescence correlation spectroscopy (FCS) modules. Here the authors present a compact, cheap and open-source 3D-printed confocal microscope for single photon counting and FCS measurements, and use it to detect α-s...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	James W. P. Brown, Arnaud Bauer, Mark E Polinkovsky, Akshay Bhumkar, Dominic J. B. Hunter, Katharina Gaus, Emma Sierecki, Yann Gambin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9dbd763de888423491044a480dfdd1b9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9dbd763de888423491044a480dfdd1b9
record_format	dspace
spelling	oai:doaj.org-article:9dbd763de888423491044a480dfdd1b92021-12-02T15:35:50ZSingle-molecule detection on a portable 3D-printed microscope10.1038/s41467-019-13617-02041-1723https://doaj.org/article/9dbd763de888423491044a480dfdd1b92019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13617-0https://doaj.org/toc/2041-1723Single-molecule in vitro assays require dedicated confocal microscopes equipped with fluorescence correlation spectroscopy (FCS) modules. Here the authors present a compact, cheap and open-source 3D-printed confocal microscope for single photon counting and FCS measurements, and use it to detect α-synuclein aggregation.James W. P. BrownArnaud BauerMark E PolinkovskyAkshay BhumkarDominic J. B. HunterKatharina GausEmma SiereckiYann GambinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James W. P. Brown Arnaud Bauer Mark E Polinkovsky Akshay Bhumkar Dominic J. B. Hunter Katharina Gaus Emma Sierecki Yann Gambin Single-molecule detection on a portable 3D-printed microscope
description	Single-molecule in vitro assays require dedicated confocal microscopes equipped with fluorescence correlation spectroscopy (FCS) modules. Here the authors present a compact, cheap and open-source 3D-printed confocal microscope for single photon counting and FCS measurements, and use it to detect α-synuclein aggregation.
format	article
author	James W. P. Brown Arnaud Bauer Mark E Polinkovsky Akshay Bhumkar Dominic J. B. Hunter Katharina Gaus Emma Sierecki Yann Gambin
author_facet	James W. P. Brown Arnaud Bauer Mark E Polinkovsky Akshay Bhumkar Dominic J. B. Hunter Katharina Gaus Emma Sierecki Yann Gambin
author_sort	James W. P. Brown
title	Single-molecule detection on a portable 3D-printed microscope
title_short	Single-molecule detection on a portable 3D-printed microscope
title_full	Single-molecule detection on a portable 3D-printed microscope
title_fullStr	Single-molecule detection on a portable 3D-printed microscope
title_full_unstemmed	Single-molecule detection on a portable 3D-printed microscope
title_sort	single-molecule detection on a portable 3d-printed microscope
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9dbd763de888423491044a480dfdd1b9
work_keys_str_mv	AT jameswpbrown singlemoleculedetectiononaportable3dprintedmicroscope AT arnaudbauer singlemoleculedetectiononaportable3dprintedmicroscope AT markepolinkovsky singlemoleculedetectiononaportable3dprintedmicroscope AT akshaybhumkar singlemoleculedetectiononaportable3dprintedmicroscope AT dominicjbhunter singlemoleculedetectiononaportable3dprintedmicroscope AT katharinagaus singlemoleculedetectiononaportable3dprintedmicroscope AT emmasierecki singlemoleculedetectiononaportable3dprintedmicroscope AT yanngambin singlemoleculedetectiononaportable3dprintedmicroscope
_version_	1718386429304766464

Single-molecule detection on a portable 3D-printed microscope

Ejemplares similares