Microbiome Analysis of Mucosal Ileoanal Pouch in Ulcerative Colitis Patients Revealed Impairment of the Pouches Immunometabolites

Microbiome Analysis of Mucosal Ileoanal Pouch in Ulcerative Colitis Patients Revealed Impairment of the Pouches Immunometabolites

The pathogenesis of ulcerative colitis (UC) is unknown, although genetic loci and altered gut microbiota have been implicated. Up to a third of patients with moderate to severe UC require proctocolectomy with ileal pouch ano-anastomosis (IPAA). We aimed to explore the mucosal microbiota of UC patien...

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Autores principales: Orazio Palmieri, Stefano Castellana, Giuseppe Biscaglia, Anna Panza, Anna Latiano, Rosanna Fontana, Maria Guerra, Giuseppe Corritore, Tiziana Latiano, Giuseppina Martino, Tommaso Mazza, Angelo Andriulli, Francesco Perri, Fabrizio Bossa
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
ulcerative colitis (UC)
IBD
IPAA
pouch
pouchitis
microbiota
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/9dbf4f34c366414090a026ca87cc603f
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