Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

Actin and microtubules play important roles in Golgi structure and function but how they are connected is poorly understood. Here the authors show that KIF20A is involved in the fission process and, in association with Myosin II, serves to anchor RAB6 on Golgi/TGN membranes near microtubules nucleat...

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Autores principales:	Stéphanie Miserey-Lenkei, Hugo Bousquet, Olena Pylypenko, Sabine Bardin, Ariane Dimitrov, Gaëlle Bressanelli, Raja Bonifay, Vincent Fraisier, Catherine Guillou, Cécile Bougeret, Anne Houdusse, Arnaud Echard, Bruno Goud
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9dec3715200e4c6c8d719f6ec478a13a
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spelling	oai:doaj.org-article:9dec3715200e4c6c8d719f6ec478a13a2021-12-02T15:38:53ZCoupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions10.1038/s41467-017-01266-02041-1723https://doaj.org/article/9dec3715200e4c6c8d719f6ec478a13a2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01266-0https://doaj.org/toc/2041-1723Actin and microtubules play important roles in Golgi structure and function but how they are connected is poorly understood. Here the authors show that KIF20A is involved in the fission process and, in association with Myosin II, serves to anchor RAB6 on Golgi/TGN membranes near microtubules nucleating sites.Stéphanie Miserey-LenkeiHugo BousquetOlena PylypenkoSabine BardinAriane DimitrovGaëlle BressanelliRaja BonifayVincent FraisierCatherine GuillouCécile BougeretAnne HoudusseArnaud EchardBruno GoudNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stéphanie Miserey-Lenkei Hugo Bousquet Olena Pylypenko Sabine Bardin Ariane Dimitrov Gaëlle Bressanelli Raja Bonifay Vincent Fraisier Catherine Guillou Cécile Bougeret Anne Houdusse Arnaud Echard Bruno Goud Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
description	Actin and microtubules play important roles in Golgi structure and function but how they are connected is poorly understood. Here the authors show that KIF20A is involved in the fission process and, in association with Myosin II, serves to anchor RAB6 on Golgi/TGN membranes near microtubules nucleating sites.
format	article
author	Stéphanie Miserey-Lenkei Hugo Bousquet Olena Pylypenko Sabine Bardin Ariane Dimitrov Gaëlle Bressanelli Raja Bonifay Vincent Fraisier Catherine Guillou Cécile Bougeret Anne Houdusse Arnaud Echard Bruno Goud
author_facet	Stéphanie Miserey-Lenkei Hugo Bousquet Olena Pylypenko Sabine Bardin Ariane Dimitrov Gaëlle Bressanelli Raja Bonifay Vincent Fraisier Catherine Guillou Cécile Bougeret Anne Houdusse Arnaud Echard Bruno Goud
author_sort	Stéphanie Miserey-Lenkei
title	Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
title_short	Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
title_full	Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
title_fullStr	Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
title_full_unstemmed	Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
title_sort	coupling fission and exit of rab6 vesicles at golgi hotspots through kinesin-myosin interactions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9dec3715200e4c6c8d719f6ec478a13a
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Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

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