Implications for breast cancer dormancy in other areas of medicine

Pranela RameshwarNew Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USABanys et al1 discussed the different viewpoints of breast cancer dormancy; albeit those that are supported by science. This editorial comments on the clinical implications of existing dorma...

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Autor principal: Rameshwar P
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Publicado: Dove Medical Press 2012
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Acceso en línea:https://doaj.org/article/9ded3d6e05904f94b49c49be05877f8e
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spelling oai:doaj.org-article:9ded3d6e05904f94b49c49be05877f8e2021-12-02T07:48:02ZImplications for breast cancer dormancy in other areas of medicine1179-1314https://doaj.org/article/9ded3d6e05904f94b49c49be05877f8e2012-12-01T00:00:00Zhttp://www.dovepress.com/implications-for-breast-cancer-dormancy-in-other-areas-of-medicine-a11677https://doaj.org/toc/1179-1314Pranela RameshwarNew Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USABanys et al1 discussed the different viewpoints of breast cancer dormancy; albeit those that are supported by science. This editorial comments on the clinical implications of existing dormant cancer cells, including future decisions to treat with stem cells.Braun et al2 reported that in cases where metastasis of breast cancer occurred in the bone marrow, this resulted in poor prognosis. As discussed by the authors, it is unclear whether breast cancer cells show tropism for an organ, or whether the cells are able to survive in a particular organ because of support from the microenvironment. Perhaps answers to this question might be clearer if a hierarchy of breast cancer cells is developed, beginning with the cancer stem cell. Depending on the cell subset, there might be a different mechanism for dormancy in an organ.Rameshwar PDove Medical PressarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol 2012, Iss default, Pp 193-195 (2012)
institution DOAJ
collection DOAJ
language EN
topic Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Rameshwar P
Implications for breast cancer dormancy in other areas of medicine
description Pranela RameshwarNew Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USABanys et al1 discussed the different viewpoints of breast cancer dormancy; albeit those that are supported by science. This editorial comments on the clinical implications of existing dormant cancer cells, including future decisions to treat with stem cells.Braun et al2 reported that in cases where metastasis of breast cancer occurred in the bone marrow, this resulted in poor prognosis. As discussed by the authors, it is unclear whether breast cancer cells show tropism for an organ, or whether the cells are able to survive in a particular organ because of support from the microenvironment. Perhaps answers to this question might be clearer if a hierarchy of breast cancer cells is developed, beginning with the cancer stem cell. Depending on the cell subset, there might be a different mechanism for dormancy in an organ.
format article
author Rameshwar P
author_facet Rameshwar P
author_sort Rameshwar P
title Implications for breast cancer dormancy in other areas of medicine
title_short Implications for breast cancer dormancy in other areas of medicine
title_full Implications for breast cancer dormancy in other areas of medicine
title_fullStr Implications for breast cancer dormancy in other areas of medicine
title_full_unstemmed Implications for breast cancer dormancy in other areas of medicine
title_sort implications for breast cancer dormancy in other areas of medicine
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/9ded3d6e05904f94b49c49be05877f8e
work_keys_str_mv AT rameshwarp implicationsforbreastcancerdormancyinotherareasofmedicine
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