Nano-BaSO4: a novel antimicrobial additive to pellethane

George E Aninwene II,1 David Stout,2 Zifan Yang,2 Thomas J Webster11Program in Bioengineering and Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 2School of Engineering, Brown University, Providence, RI, USAAbstract: Hospital-acquired infections remain a costly clinical...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Aninwene II GE, Stout D, Yang Z, Webster TJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9df31590dcd54b2896fb13fce64149c6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9df31590dcd54b2896fb13fce64149c6
record_format	dspace
spelling	oai:doaj.org-article:9df31590dcd54b2896fb13fce64149c62021-12-02T02:31:47ZNano-BaSO4: a novel antimicrobial additive to pellethane1176-91141178-2013https://doaj.org/article/9df31590dcd54b2896fb13fce64149c62013-03-01T00:00:00Zhttp://www.dovepress.com/nano-baso4-a-novel-antimicrobial-additive-to-pellethane-a12545https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013George E Aninwene II,1 David Stout,2 Zifan Yang,2 Thomas J Webster11Program in Bioengineering and Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 2School of Engineering, Brown University, Providence, RI, USAAbstract: Hospital-acquired infections remain a costly clinical problem. Barium sulfate (BaSO4, in micron particulate form) is a common radiopacifying agent that is added to catheters and endotracheal tubes. Due to the recently observed ability of nanostructured surface features to decrease functions of bacteria without the aid of antibiotics, the objective of this in vitro study was to incorporate nano-barium sulfate into pellethane and determine the antimicrobial properties of the resulting composites. The results demonstrated for the first time that the incorporation of nano-barium sulfate into pellethane enhanced antimicrobial properties (using Staphylococcus aureus and Pseudomonas aeruginosa) compared to currently used pellethane; properties that warrant further investigation for a wide range of clinical applications.Keywords: antimicrobial polymer, hospital-acquired infections, surface roughness, radiopaque agent, dynamic contact microbial testingAninwene II GEStout DYang ZWebster TJDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss default, Pp 1197-1205 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Aninwene II GE Stout D Yang Z Webster TJ Nano-BaSO4: a novel antimicrobial additive to pellethane
description	George E Aninwene II,1 David Stout,2 Zifan Yang,2 Thomas J Webster11Program in Bioengineering and Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 2School of Engineering, Brown University, Providence, RI, USAAbstract: Hospital-acquired infections remain a costly clinical problem. Barium sulfate (BaSO4, in micron particulate form) is a common radiopacifying agent that is added to catheters and endotracheal tubes. Due to the recently observed ability of nanostructured surface features to decrease functions of bacteria without the aid of antibiotics, the objective of this in vitro study was to incorporate nano-barium sulfate into pellethane and determine the antimicrobial properties of the resulting composites. The results demonstrated for the first time that the incorporation of nano-barium sulfate into pellethane enhanced antimicrobial properties (using Staphylococcus aureus and Pseudomonas aeruginosa) compared to currently used pellethane; properties that warrant further investigation for a wide range of clinical applications.Keywords: antimicrobial polymer, hospital-acquired infections, surface roughness, radiopaque agent, dynamic contact microbial testing
format	article
author	Aninwene II GE Stout D Yang Z Webster TJ
author_facet	Aninwene II GE Stout D Yang Z Webster TJ
author_sort	Aninwene II GE
title	Nano-BaSO4: a novel antimicrobial additive to pellethane
title_short	Nano-BaSO4: a novel antimicrobial additive to pellethane
title_full	Nano-BaSO4: a novel antimicrobial additive to pellethane
title_fullStr	Nano-BaSO4: a novel antimicrobial additive to pellethane
title_full_unstemmed	Nano-BaSO4: a novel antimicrobial additive to pellethane
title_sort	nano-baso4: a novel antimicrobial additive to pellethane
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/9df31590dcd54b2896fb13fce64149c6
work_keys_str_mv	AT aninweneiige nanobaso4anovelantimicrobialadditivetopellethane AT stoutd nanobaso4anovelantimicrobialadditivetopellethane AT yangz nanobaso4anovelantimicrobialadditivetopellethane AT webstertj nanobaso4anovelantimicrobialadditivetopellethane
_version_	1718402426679066624

Nano-BaSO4: a novel antimicrobial additive to pellethane

Ejemplares similares