The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis.
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Nature Portfolio
2019
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oai:doaj.org-article:9df5e81462244de79050645d220e8ebe2021-12-02T17:02:10ZThe Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis10.1038/s41467-019-09009-z2041-1723https://doaj.org/article/9df5e81462244de79050645d220e8ebe2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09009-zhttps://doaj.org/toc/2041-1723Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis.Saoirse S. McSharryGreg J. BeitelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Saoirse S. McSharry Greg J. Beitel The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis |
description |
Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis. |
format |
article |
author |
Saoirse S. McSharry Greg J. Beitel |
author_facet |
Saoirse S. McSharry Greg J. Beitel |
author_sort |
Saoirse S. McSharry |
title |
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis |
title_short |
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis |
title_full |
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis |
title_fullStr |
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis |
title_full_unstemmed |
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis |
title_sort |
caspase-3 homolog drice regulates endocytic trafficking during drosophila tracheal morphogenesis |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/9df5e81462244de79050645d220e8ebe |
work_keys_str_mv |
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_version_ |
1718381986395979776 |