The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis

Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis.

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Autores principales: Saoirse S. McSharry, Greg J. Beitel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9df5e81462244de79050645d220e8ebe
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spelling oai:doaj.org-article:9df5e81462244de79050645d220e8ebe2021-12-02T17:02:10ZThe Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis10.1038/s41467-019-09009-z2041-1723https://doaj.org/article/9df5e81462244de79050645d220e8ebe2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09009-zhttps://doaj.org/toc/2041-1723Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis.Saoirse S. McSharryGreg J. BeitelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Saoirse S. McSharry
Greg J. Beitel
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
description Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis.
format article
author Saoirse S. McSharry
Greg J. Beitel
author_facet Saoirse S. McSharry
Greg J. Beitel
author_sort Saoirse S. McSharry
title The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
title_short The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
title_full The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
title_fullStr The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
title_full_unstemmed The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis
title_sort caspase-3 homolog drice regulates endocytic trafficking during drosophila tracheal morphogenesis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9df5e81462244de79050645d220e8ebe
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