Atomic force microscopy probing in the measurement of cell mechanics

Dimitrios Kirmizis, Stergios LogothetidisDepartment of Physics, Laboratory for Thin Films-Nanosystems and Nanometrology, Aristotle University, Thessaloniki, GreeceAbstract: Atomic force microscope (AFM) has been used incrementally over the last decade in cell biology. Beyond its usefulness in high r...

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Autores principales:	Dimitrios Kirmizis, Stergios Logothetidis
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9dfa35cfb47e41858f4674e933a2634d
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spelling	oai:doaj.org-article:9dfa35cfb47e41858f4674e933a2634d2021-12-02T01:30:29ZAtomic force microscopy probing in the measurement of cell mechanics1176-91141178-2013https://doaj.org/article/9dfa35cfb47e41858f4674e933a2634d2010-03-01T00:00:00Zhttp://www.dovepress.com/atomic-force-microscopy-probing-in-the-measurement-of-cell-mechanics-a4112https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Dimitrios Kirmizis, Stergios LogothetidisDepartment of Physics, Laboratory for Thin Films-Nanosystems and Nanometrology, Aristotle University, Thessaloniki, GreeceAbstract: Atomic force microscope (AFM) has been used incrementally over the last decade in cell biology. Beyond its usefulness in high resolution imaging, AFM also has unique capabilities for probing the viscoelastic properties of living cells in culture and, even more, mapping the spatial distribution of cell mechanical properties, providing thus an indirect indicator of the structure and function of the underlying cytoskeleton and cell organelles. AFM measurements have boosted our understanding of cell mechanics in normal and diseased states and provide future potential in the study of disease pathophysiology and in the establishment of novel diagnostic and treatment options.Keywords: atomic force microscopy, cell mechanics, cell elastography, cell force spectroscopy Dimitrios KirmizisStergios LogothetidisDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2010, Iss default, Pp 137-145 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Dimitrios Kirmizis Stergios Logothetidis Atomic force microscopy probing in the measurement of cell mechanics
description	Dimitrios Kirmizis, Stergios LogothetidisDepartment of Physics, Laboratory for Thin Films-Nanosystems and Nanometrology, Aristotle University, Thessaloniki, GreeceAbstract: Atomic force microscope (AFM) has been used incrementally over the last decade in cell biology. Beyond its usefulness in high resolution imaging, AFM also has unique capabilities for probing the viscoelastic properties of living cells in culture and, even more, mapping the spatial distribution of cell mechanical properties, providing thus an indirect indicator of the structure and function of the underlying cytoskeleton and cell organelles. AFM measurements have boosted our understanding of cell mechanics in normal and diseased states and provide future potential in the study of disease pathophysiology and in the establishment of novel diagnostic and treatment options.Keywords: atomic force microscopy, cell mechanics, cell elastography, cell force spectroscopy
format	article
author	Dimitrios Kirmizis Stergios Logothetidis
author_facet	Dimitrios Kirmizis Stergios Logothetidis
author_sort	Dimitrios Kirmizis
title	Atomic force microscopy probing in the measurement of cell mechanics
title_short	Atomic force microscopy probing in the measurement of cell mechanics
title_full	Atomic force microscopy probing in the measurement of cell mechanics
title_fullStr	Atomic force microscopy probing in the measurement of cell mechanics
title_full_unstemmed	Atomic force microscopy probing in the measurement of cell mechanics
title_sort	atomic force microscopy probing in the measurement of cell mechanics
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/9dfa35cfb47e41858f4674e933a2634d
work_keys_str_mv	AT dimitrioskirmizis atomicforcemicroscopyprobinginthemeasurementofcellmechanics AT stergioslogothetidis atomicforcemicroscopyprobinginthemeasurementofcellmechanics
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Atomic force microscopy probing in the measurement of cell mechanics

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