Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice

The rTg4510 mosue line has a tauopathy-like phenotype which is attributed to overexpression of human tau in the frontal cortex. Here the authors identify potential confounding genetic factors that could contribute to the phenotype.

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Autores principales:	Julia Gamache, Kellie Benzow, Colleen Forster, Lisa Kemper, Chris Hlynialuk, Eva Furrow, Karen H. Ashe, Michael D. Koob
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e0243c9022847c19c905619188b6933
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spelling	oai:doaj.org-article:9e0243c9022847c19c905619188b69332021-12-02T15:35:53ZFactors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice10.1038/s41467-019-10428-12041-1723https://doaj.org/article/9e0243c9022847c19c905619188b69332019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10428-1https://doaj.org/toc/2041-1723The rTg4510 mosue line has a tauopathy-like phenotype which is attributed to overexpression of human tau in the frontal cortex. Here the authors identify potential confounding genetic factors that could contribute to the phenotype.Julia GamacheKellie BenzowColleen ForsterLisa KemperChris HlynialukEva FurrowKaren H. AsheMichael D. KoobNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julia Gamache Kellie Benzow Colleen Forster Lisa Kemper Chris Hlynialuk Eva Furrow Karen H. Ashe Michael D. Koob Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
description	The rTg4510 mosue line has a tauopathy-like phenotype which is attributed to overexpression of human tau in the frontal cortex. Here the authors identify potential confounding genetic factors that could contribute to the phenotype.
format	article
author	Julia Gamache Kellie Benzow Colleen Forster Lisa Kemper Chris Hlynialuk Eva Furrow Karen H. Ashe Michael D. Koob
author_facet	Julia Gamache Kellie Benzow Colleen Forster Lisa Kemper Chris Hlynialuk Eva Furrow Karen H. Ashe Michael D. Koob
author_sort	Julia Gamache
title	Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
title_short	Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
title_full	Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
title_fullStr	Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
title_full_unstemmed	Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
title_sort	factors other than htau overexpression that contribute to tauopathy-like phenotype in rtg4510 mice
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9e0243c9022847c19c905619188b6933
work_keys_str_mv	AT juliagamache factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT kelliebenzow factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT colleenforster factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT lisakemper factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT chrishlynialuk factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT evafurrow factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT karenhashe factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice AT michaeldkoob factorsotherthanhtauoverexpressionthatcontributetotauopathylikephenotypeinrtg4510mice
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Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice

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