Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus.

Smallpox, caused by the solely human pathogen Variola virus (VARV), was declared eradicated in 1980. While known VARV stocks are secure, smallpox remains a bioterrorist threat agent. Recent U.S. Food and Drug Administration approval of the first smallpox anti-viral (tecovirimat) therapeutic was a su...

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Autores principales: Christina L Hutson, Ashley V Kondas, Jana M Ritter, Zachary Reed, Sharon Dietz Ostergaard, Clint N Morgan, Nadia Gallardo-Romero, Cassandra Tansey, Matthew R Mauldin, Johanna S Salzer, Christine M Hughes, Cynthia S Goldsmith, Darin Carroll, Victoria A Olson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/9e0446caa7794c65aa4b99c44e348d8c
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