The retinoid X receptor α modulator K-80003 suppresses inflammatory and catabolic responses in a rat model of osteoarthritis

Abstract Osteoarthritis (OA), a most common and highly prevalent joint disease, is closely associated with dysregulated expression and modification of RXRα. However, the role of RXRα in the pathophysiology of OA remains unknown. The present study aimed to investigate whether RXRα modulator, such as...

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Autores principales: Hua Li, Xiaofan Li, Boyu Yang, Junnan Su, Shaofang Cai, Jinmei Huang, Tianfu Hu, Lijuan Chen, Yaping Xu, Yuhang Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9e0d7c2344b2477da01685fc12d0f190
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