Molecular basis of essential thrombocythaemia in humans and dogs – a review

<b>A potential cause of essential thrombocythaemia can be seen as the V617F point mutation within Janus kinase 2. This mutation occurs in 60-70% of patients with this disease and is located in the domain acting as an inhibitor. It increases the enzymatic activity of JAK2 kinase and induces int...

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Autores principales: Nicola Padzik, Małgorzata Szewczuk
Formato: article
Lenguaje:EN
PL
Publicado: Polish Society of Animal Production 2021
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Acceso en línea:https://doaj.org/article/9e1699cfd2e84ec78f01867596a1f248
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