Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

Spermatogonia establishment in the fetal and postnatal period is essential for spermatozoa production. Here the authors present a protocol for in vitro reconstitution of human prospermatogonial specification and perform single cell RNA-sequencing to delineate lineage trajectories.

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Autores principales: Young Sun Hwang, Shinnosuke Suzuki, Yasunari Seita, Jumpei Ito, Yuka Sakata, Hirofumi Aso, Kei Sato, Brian P. Hermann, Kotaro Sasaki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/9e1796a5969343aa9d6112aa30c1ceec
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