Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat

Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat

Brown adipocytes contribute to energy balance, and adipocyte development and brown adipocyte thermogenesis are in part regulated by epigenetic modifications. Here the authors report that the histone demethylase Utx maintains brown adipocyte identity via demethylation of PRDM16, which in turn repress...

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Autores principales: Fenfen Li, Jia Jing, Miranda Movahed, Xin Cui, Qiang Cao, Rui Wu, Ziyue Chen, Liqing Yu, Yi Pan, Huidong Shi, Hang Shi, Bingzhong Xue
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/9e1c665d859844b1bc78ae334cecc799
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