Curcumin alleviates diabetic nephropathy via inhibiting podocyte mesenchymal transdifferentiation and inducing autophagy in rats and MPC5 cells
Context: Curcumin could ameliorate diabetic nephropathy (DN), but the mechanism remains unclear. Objective: The efficacy of curcumin on epithelial-to-mesenchymal transition (EMT) of podocyte and autophagy in vivo and in vitro was explored. Materials and methods: Thirty male Sprague–Dawley rats were...
Guardado en:
Autores principales: | Qiudi Tu, Yiwen Li, Juan Jin, Xinxin Jiang, Yan Ren, Qiang He |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9e212d5ebc144bfcb89067838fd87d8a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Baicalin improves podocyte injury in rats with diabetic nephropathy by inhibiting PI3K/Akt/mTOR signaling pathway
por: Ou Yi, et al.
Publicado: (2021) -
Epidermal Growth Factor Protects Against High Glucose-Induced Podocyte Injury Possibly via Modulation of Autophagy and PI3K/AKT/mTOR Signaling Pathway Through DNA Methylation
por: Sun Y, et al.
Publicado: (2021) -
Curcumin Inhibited Podocyte Cell Apoptosis and Accelerated Cell Autophagy in Diabetic Nephropathy via Regulating Beclin1/UVRAG/Bcl2
por: Zhang P, et al.
Publicado: (2020) -
Calpain-10 drives podocyte apoptosis and renal injury in diabetic nephropathy
por: Wang T, et al.
Publicado: (2019) -
Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis
por: Runze Zhang, et al.
Publicado: (2021)