Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures

Chiroptical sensing in complex mixtures remains a challenging task. Here, the authors report an efficient coumarin probe for chiroptical click chirality sensing of absolute configuration, concentration and enantiomeric excess of several compound classes. The method can be directly applied to crude a...

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Autores principales:	F. Yushra Thanzeel, Kaluvu Balaraman, Christian Wolf
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e229cd68b9242ebba5443dd7c4b908f
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spelling	oai:doaj.org-article:9e229cd68b9242ebba5443dd7c4b908f2021-12-02T15:34:02ZClick chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures10.1038/s41467-018-07695-92041-1723https://doaj.org/article/9e229cd68b9242ebba5443dd7c4b908f2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07695-9https://doaj.org/toc/2041-1723Chiroptical sensing in complex mixtures remains a challenging task. Here, the authors report an efficient coumarin probe for chiroptical click chirality sensing of absolute configuration, concentration and enantiomeric excess of several compound classes. The method can be directly applied to crude asymmetric reaction mixtures.F. Yushra ThanzeelKaluvu BalaramanChristian WolfNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q F. Yushra Thanzeel Kaluvu Balaraman Christian Wolf Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
description	Chiroptical sensing in complex mixtures remains a challenging task. Here, the authors report an efficient coumarin probe for chiroptical click chirality sensing of absolute configuration, concentration and enantiomeric excess of several compound classes. The method can be directly applied to crude asymmetric reaction mixtures.
format	article
author	F. Yushra Thanzeel Kaluvu Balaraman Christian Wolf
author_facet	F. Yushra Thanzeel Kaluvu Balaraman Christian Wolf
author_sort	F. Yushra Thanzeel
title	Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
title_short	Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
title_full	Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
title_fullStr	Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
title_full_unstemmed	Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
title_sort	click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9e229cd68b9242ebba5443dd7c4b908f
work_keys_str_mv	AT fyushrathanzeel clickchemistryenablesquantitativechiropticalsensingofchiralcompoundsinproticmediaandcomplexmixtures AT kaluvubalaraman clickchemistryenablesquantitativechiropticalsensingofchiralcompoundsinproticmediaandcomplexmixtures AT christianwolf clickchemistryenablesquantitativechiropticalsensingofchiralcompoundsinproticmediaandcomplexmixtures
_version_	1718386979970744320

Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures

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