Evaluation of connectivity map shows limited reproducibility in drug repositioning
Abstract The Connectivity Map (CMap) is a popular resource designed for data-driven drug repositioning using a large transcriptomic compendium. However, evaluations of its performance are limited. We used two iterations of CMap (CMap 1 and 2) to assess their comparability and reliability. We queried...
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Main Authors: | Nathaniel Lim, Paul Pavlidis |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/9e2c9782c48e4f3c8dd4b0ba6b14221c |
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