Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels

Complex RNA three-dimensional structures undergo functionally important programmed conformational changes. Here, the authors report how two structurally and functionally coupled RNA domains within a viral 3′-UTR sense the ribosome through conformational changes and respond by modulating translation....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Erik W. Hartwick, David A. Costantino, Andrea MacFadden, Jay C. Nix, Siqi Tian, Rhiju Das, Jeffrey S. Kieft
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e3575109598441c9bf349e416a47825
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9e3575109598441c9bf349e416a47825
record_format	dspace
spelling	oai:doaj.org-article:9e3575109598441c9bf349e416a478252021-12-02T17:33:18ZRibosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels10.1038/s41467-018-07542-x2041-1723https://doaj.org/article/9e3575109598441c9bf349e416a478252018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07542-xhttps://doaj.org/toc/2041-1723Complex RNA three-dimensional structures undergo functionally important programmed conformational changes. Here, the authors report how two structurally and functionally coupled RNA domains within a viral 3′-UTR sense the ribosome through conformational changes and respond by modulating translation.Erik W. HartwickDavid A. CostantinoAndrea MacFaddenJay C. NixSiqi TianRhiju DasJeffrey S. KieftNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erik W. Hartwick David A. Costantino Andrea MacFadden Jay C. Nix Siqi Tian Rhiju Das Jeffrey S. Kieft Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
description	Complex RNA three-dimensional structures undergo functionally important programmed conformational changes. Here, the authors report how two structurally and functionally coupled RNA domains within a viral 3′-UTR sense the ribosome through conformational changes and respond by modulating translation.
format	article
author	Erik W. Hartwick David A. Costantino Andrea MacFadden Jay C. Nix Siqi Tian Rhiju Das Jeffrey S. Kieft
author_facet	Erik W. Hartwick David A. Costantino Andrea MacFadden Jay C. Nix Siqi Tian Rhiju Das Jeffrey S. Kieft
author_sort	Erik W. Hartwick
title	Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
title_short	Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
title_full	Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
title_fullStr	Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
title_full_unstemmed	Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
title_sort	ribosome-induced rna conformational changes in a viral 3′-utr sense and regulate translation levels
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9e3575109598441c9bf349e416a47825
work_keys_str_mv	AT erikwhartwick ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels AT davidacostantino ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels AT andreamacfadden ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels AT jaycnix ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels AT siqitian ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels AT rhijudas ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels AT jeffreyskieft ribosomeinducedrnaconformationalchangesinaviral3utrsenseandregulatetranslationlevels
_version_	1718380014869676032

Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels

Ejemplares similares