Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels

Complex RNA three-dimensional structures undergo functionally important programmed conformational changes. Here, the authors report how two structurally and functionally coupled RNA domains within a viral 3′-UTR sense the ribosome through conformational changes and respond by modulating translation....

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Autores principales: Erik W. Hartwick, David A. Costantino, Andrea MacFadden, Jay C. Nix, Siqi Tian, Rhiju Das, Jeffrey S. Kieft
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9e3575109598441c9bf349e416a47825
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