The non-canonical Wnt/PKC pathway regulates mitochondrial dynamics through degradation of the arm-like domain-containing protein Alex3.
The regulation of mitochondrial dynamics is vital in complex cell types, such as neurons, that transport and localize mitochondria in high energy-demanding cell domains. The Armcx3 gene encodes a mitochondrial-targeted protein (Alex3) that contains several arm-like domains. In a previous study we sh...
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Auteurs principaux: | Román Serrat, Guillermo López-Doménech, Serena Mirra, Martí Quevedo, Jordi Garcia-Fernàndez, Fausto Ulloa, Ferrán Burgaya, Eduardo Soriano |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/9e3780b8f9ac47d199e80d9791b94e0d |
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