The non-canonical Wnt/PKC pathway regulates mitochondrial dynamics through degradation of the arm-like domain-containing protein Alex3.

The regulation of mitochondrial dynamics is vital in complex cell types, such as neurons, that transport and localize mitochondria in high energy-demanding cell domains. The Armcx3 gene encodes a mitochondrial-targeted protein (Alex3) that contains several arm-like domains. In a previous study we sh...

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Auteurs principaux: Román Serrat, Guillermo López-Doménech, Serena Mirra, Martí Quevedo, Jordi Garcia-Fernàndez, Fausto Ulloa, Ferrán Burgaya, Eduardo Soriano
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/9e3780b8f9ac47d199e80d9791b94e0d
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