Evaluation of UBE3A antibodies in mice and human cerebral organoids

Abstract UBE3A is an E3 ubiquitin ligase encoded by the neurally imprinted UBE3A gene. The abundance and subcellular distribution of UBE3A has been the topic of many previous studies as its dosage and localization has been linked to neurodevelopmental disorders including Autism, Dup15q syndrome, and...

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Autores principales: Dilara Sen, Zuzana Drobna, Albert J. Keung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9e387ac290914899a72d3d48062a092f
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