Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress

Various pathologies, in particular hypertension, accompany violation of the processes of free radical oxidation. The state of the system lipid peroxidation – antioxidant protection can be assessed only by a complex of biochemical methods. The chemiluminescent method is used to obtain a faster result...

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Autores principales:	Anastasiya S. Brichagina, Mariya I. Dolgikh, Larisa R. Kolesnikova, Larisa V. Natyaganova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	chemiluminescence oxidative stress isiah rats arterial hypertension Science Q
Acceso en línea:	https://doaj.org/article/9e47fbfde5b344a5af70439c064992ea
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spelling	oai:doaj.org-article:9e47fbfde5b344a5af70439c064992ea2021-11-23T06:14:42ZChemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress2541-94202587-959610.29413/ABS.2019-4.1.20https://doaj.org/article/9e47fbfde5b344a5af70439c064992ea2019-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1990https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Various pathologies, in particular hypertension, accompany violation of the processes of free radical oxidation. The state of the system lipid peroxidation – antioxidant protection can be assessed only by a complex of biochemical methods. The chemiluminescent method is used to obtain a faster result. The method has a number of advantages: measurement of chemiluminescence parameters is carried out in natural conditions and does not require sample preparation, is highly selective, it can be used to identify the presence of free radical pathology, analysis of the intensity of lipid peroxidation processes, the effectiveness of treatment with antioxidant medicament. The aim of the research was to study the lipid peroxidation under hypertension and stress by chemiluminescence. The experiment was conducted on male rats of the ISIAH line. The experiment consisted of 2 stages: stage of alarm and stage of chronic stress. We found that, depending on the type of stress, the state of the system lipid peroxidation-antioxidant protection differed. The role of stress in violation of the processes of lipoperoxidation in hypertension was established. The efficacy of the chemiluminescence method as an alternative to a complex of biochemical methods is shown. Express assessment of pro- and antioxidant status is possible for patients with hypertension.Anastasiya S. BrichaginaMariya I. DolgikhLarisa R. KolesnikovaLarisa V. NatyaganovaScientific Сentre for Family Health and Human Reproduction Problemsarticlechemiluminescenceoxidative stressisiah ratsarterial hypertensionScienceQRUActa Biomedica Scientifica, Vol 4, Iss 1, Pp 133-137 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	chemiluminescence oxidative stress isiah rats arterial hypertension Science Q
spellingShingle	chemiluminescence oxidative stress isiah rats arterial hypertension Science Q Anastasiya S. Brichagina Mariya I. Dolgikh Larisa R. Kolesnikova Larisa V. Natyaganova Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress
description	Various pathologies, in particular hypertension, accompany violation of the processes of free radical oxidation. The state of the system lipid peroxidation – antioxidant protection can be assessed only by a complex of biochemical methods. The chemiluminescent method is used to obtain a faster result. The method has a number of advantages: measurement of chemiluminescence parameters is carried out in natural conditions and does not require sample preparation, is highly selective, it can be used to identify the presence of free radical pathology, analysis of the intensity of lipid peroxidation processes, the effectiveness of treatment with antioxidant medicament. The aim of the research was to study the lipid peroxidation under hypertension and stress by chemiluminescence. The experiment was conducted on male rats of the ISIAH line. The experiment consisted of 2 stages: stage of alarm and stage of chronic stress. We found that, depending on the type of stress, the state of the system lipid peroxidation-antioxidant protection differed. The role of stress in violation of the processes of lipoperoxidation in hypertension was established. The efficacy of the chemiluminescence method as an alternative to a complex of biochemical methods is shown. Express assessment of pro- and antioxidant status is possible for patients with hypertension.
format	article
author	Anastasiya S. Brichagina Mariya I. Dolgikh Larisa R. Kolesnikova Larisa V. Natyaganova
author_facet	Anastasiya S. Brichagina Mariya I. Dolgikh Larisa R. Kolesnikova Larisa V. Natyaganova
author_sort	Anastasiya S. Brichagina
title	Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress
title_short	Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress
title_full	Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress
title_fullStr	Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress
title_full_unstemmed	Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress
title_sort	chemiluminescence studies of lipoperoxidation processes in arterial hypertension and stress
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/9e47fbfde5b344a5af70439c064992ea
work_keys_str_mv	AT anastasiyasbrichagina chemiluminescencestudiesoflipoperoxidationprocessesinarterialhypertensionandstress AT mariyaidolgikh chemiluminescencestudiesoflipoperoxidationprocessesinarterialhypertensionandstress AT larisarkolesnikova chemiluminescencestudiesoflipoperoxidationprocessesinarterialhypertensionandstress AT larisavnatyaganova chemiluminescencestudiesoflipoperoxidationprocessesinarterialhypertensionandstress
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Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress

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