Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation

This study revealed the microbial compositions in children with bacterial meningitis who were treated with antibiotics and made a comprehensive comparison between blood and CSF specimens for risk and prognosis assessment. We found that microbiome signatures could distinguish patient subsets and wer...

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Autores principales:	Huiping Liao, Yuchao Zhang, Wei Guo, Xi Wang, Hailong Wang, Haocheng Ye, Kai Wu, Yu-Hang Zhang, Lingyun Guo, Yufei Zhu, Yongli Guo, Landian Hu, Gang Liu, Xiangyin Kong
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/9e53c87cdad3470587c8c34c02f500c9
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spelling	oai:doaj.org-article:9e53c87cdad3470587c8c34c02f500c92021-12-02T18:50:25ZCharacterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation2379-507710.1128/mSystems.00049-21https://doaj.org/article/9e53c87cdad3470587c8c34c02f500c92021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00049-21https://doaj.org/toc/2379-5077 This study revealed the microbial compositions in children with bacterial meningitis who were treated with antibiotics and made a comprehensive comparison between blood and CSF specimens for risk and prognosis assessment. We found that microbiome signatures could distinguish patient subsets and were correlated with the CRP level in blood and granulocyte percentage in CSF.Huiping LiaoYuchao ZhangWei GuoXi WangHailong WangHaocheng YeKai WuYu-Hang ZhangLingyun GuoYufei ZhuYongli GuoLandian HuGang LiuXiangyin KongAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Huiping Liao Yuchao Zhang Wei Guo Xi Wang Hailong Wang Haocheng Ye Kai Wu Yu-Hang Zhang Lingyun Guo Yufei Zhu Yongli Guo Landian Hu Gang Liu Xiangyin Kong Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation
description	This study revealed the microbial compositions in children with bacterial meningitis who were treated with antibiotics and made a comprehensive comparison between blood and CSF specimens for risk and prognosis assessment. We found that microbiome signatures could distinguish patient subsets and were correlated with the CRP level in blood and granulocyte percentage in CSF.
format	article
author	Huiping Liao Yuchao Zhang Wei Guo Xi Wang Hailong Wang Haocheng Ye Kai Wu Yu-Hang Zhang Lingyun Guo Yufei Zhu Yongli Guo Landian Hu Gang Liu Xiangyin Kong
author_facet	Huiping Liao Yuchao Zhang Wei Guo Xi Wang Hailong Wang Haocheng Ye Kai Wu Yu-Hang Zhang Lingyun Guo Yufei Zhu Yongli Guo Landian Hu Gang Liu Xiangyin Kong
author_sort	Huiping Liao
title	Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation
title_short	Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation
title_full	Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation
title_fullStr	Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation
title_full_unstemmed	Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation
title_sort	characterization of the blood and cerebrospinal fluid microbiome in children with bacterial meningitis and its potential correlation with inflammation
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/9e53c87cdad3470587c8c34c02f500c9
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Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation

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