NK cells are activated and primed for skin-homing during acute dengue virus infection in humans

Here, Zimmer et al. analyze the natural killer (NK) cell response in a patient cohort with acute dengue virus infection showing early NK cell activation and proliferation, and the data suggest that NK cell proliferation depends on IL-18 signaling, and that responding NK cells have a skin-homing phen...

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Autores principales: Christine L. Zimmer, Martin Cornillet, Carles Solà-Riera, Ka-Wai Cheung, Martin A. Ivarsson, Mei Qiu Lim, Nicole Marquardt, Yee-Sin Leo, David Chien Lye, Jonas Klingström, Paul A. MacAry, Hans-Gustaf Ljunggren, Laura Rivino, Niklas K. Björkström
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9e5b6fae44fb48c5a13eee33e02cd24b
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Sumario:Here, Zimmer et al. analyze the natural killer (NK) cell response in a patient cohort with acute dengue virus infection showing early NK cell activation and proliferation, and the data suggest that NK cell proliferation depends on IL-18 signaling, and that responding NK cells have a skin-homing phenotype.