Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells

Objective. The aim of the present investigation was to study the effect of hypoxia on the expression of genes encoding endothelin-1 (EDN1) and its cognate receptors (EDNRA and EDNRB) as well as endothelin converting enzyme 1 (ECE1) in U87 glioma cells in response to inhibition of endoplasmic reticul...

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Autores principales:	Minchenko Dmytro O., Tsymbal Daria O., Riabovol Olena O., Viletska Yuliia M., Lahanovska Yuliia O., Sliusar Myroslava Y., Bezrodnyi Borys H., Minchenko Oleksandr H.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	hypoxia mrna expression edn1 ednra ednrb ece1 microrna ern1 knockdown u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/9e6224df477c4abcb3a659bbeae30b35
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id	oai:doaj.org-article:9e6224df477c4abcb3a659bbeae30b35
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spelling	oai:doaj.org-article:9e6224df477c4abcb3a659bbeae30b352021-12-02T19:07:37ZHypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells1336-032910.2478/enr-2019-0025https://doaj.org/article/9e6224df477c4abcb3a659bbeae30b352019-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0025https://doaj.org/toc/1336-0329Objective. The aim of the present investigation was to study the effect of hypoxia on the expression of genes encoding endothelin-1 (EDN1) and its cognate receptors (EDNRA and EDNRB) as well as endothelin converting enzyme 1 (ECE1) in U87 glioma cells in response to inhibition of endoplasmic reticulum stress signaling mediated by ERN1/IRE1 (endoplasmic reticulum to nucleus signaling 1) for evaluation of their possible significance in the control of glioma growth through ERN1 and hypoxia.Minchenko Dmytro O.Tsymbal Daria O.Riabovol Olena O.Viletska Yuliia M.Lahanovska Yuliia O.Sliusar Myroslava Y.Bezrodnyi Borys H.Minchenko Oleksandr H.Sciendoarticlehypoxiamrna expressionedn1ednraednrbece1micrornaern1 knockdownu87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 4, Pp 250-262 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	hypoxia mrna expression edn1 ednra ednrb ece1 microrna ern1 knockdown u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	hypoxia mrna expression edn1 ednra ednrb ece1 microrna ern1 knockdown u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Minchenko Dmytro O. Tsymbal Daria O. Riabovol Olena O. Viletska Yuliia M. Lahanovska Yuliia O. Sliusar Myroslava Y. Bezrodnyi Borys H. Minchenko Oleksandr H. Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells
description	Objective. The aim of the present investigation was to study the effect of hypoxia on the expression of genes encoding endothelin-1 (EDN1) and its cognate receptors (EDNRA and EDNRB) as well as endothelin converting enzyme 1 (ECE1) in U87 glioma cells in response to inhibition of endoplasmic reticulum stress signaling mediated by ERN1/IRE1 (endoplasmic reticulum to nucleus signaling 1) for evaluation of their possible significance in the control of glioma growth through ERN1 and hypoxia.
format	article
author	Minchenko Dmytro O. Tsymbal Daria O. Riabovol Olena O. Viletska Yuliia M. Lahanovska Yuliia O. Sliusar Myroslava Y. Bezrodnyi Borys H. Minchenko Oleksandr H.
author_facet	Minchenko Dmytro O. Tsymbal Daria O. Riabovol Olena O. Viletska Yuliia M. Lahanovska Yuliia O. Sliusar Myroslava Y. Bezrodnyi Borys H. Minchenko Oleksandr H.
author_sort	Minchenko Dmytro O.
title	Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells
title_short	Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells
title_full	Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells
title_fullStr	Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells
title_full_unstemmed	Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells
title_sort	hypoxic regulation of edn1, ednra, ednrb, and ece1 gene expressions in ern1 knockdown u87 glioma cells
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/9e6224df477c4abcb3a659bbeae30b35
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Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells

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