Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome

Analysis of virus replication on a single-cell level is often hampered by a lack of specific or sensitive enough reagents. Here, Douamet al. use RNA-flow technique to track (+) and (−) strand RNA of yellow fever virus in hematopoietic cells in mouse models and identify virus-host interactions that a...

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Autores principales:	Florian Douam, Gabriela Hrebikova, Yentli E. Soto Albrecht, Julie Sellau, Yael Sharon, Qiang Ding, Alexander Ploss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e697919b38849b796bf1377f8eb6d31
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spelling	oai:doaj.org-article:9e697919b38849b796bf1377f8eb6d312021-12-02T15:38:43ZSingle-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome10.1038/ncomms147812041-1723https://doaj.org/article/9e697919b38849b796bf1377f8eb6d312017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14781https://doaj.org/toc/2041-1723Analysis of virus replication on a single-cell level is often hampered by a lack of specific or sensitive enough reagents. Here, Douamet al. use RNA-flow technique to track (+) and (−) strand RNA of yellow fever virus in hematopoietic cells in mouse models and identify virus-host interactions that affect disease outcome.Florian DouamGabriela HrebikovaYentli E. Soto AlbrechtJulie SellauYael SharonQiang DingAlexander PlossNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Florian Douam Gabriela Hrebikova Yentli E. Soto Albrecht Julie Sellau Yael Sharon Qiang Ding Alexander Ploss Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
description	Analysis of virus replication on a single-cell level is often hampered by a lack of specific or sensitive enough reagents. Here, Douamet al. use RNA-flow technique to track (+) and (−) strand RNA of yellow fever virus in hematopoietic cells in mouse models and identify virus-host interactions that affect disease outcome.
format	article
author	Florian Douam Gabriela Hrebikova Yentli E. Soto Albrecht Julie Sellau Yael Sharon Qiang Ding Alexander Ploss
author_facet	Florian Douam Gabriela Hrebikova Yentli E. Soto Albrecht Julie Sellau Yael Sharon Qiang Ding Alexander Ploss
author_sort	Florian Douam
title	Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
title_short	Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
title_full	Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
title_fullStr	Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
title_full_unstemmed	Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
title_sort	single-cell tracking of flavivirus rna uncovers species-specific interactions with the immune system dictating disease outcome
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9e697919b38849b796bf1377f8eb6d31
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Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome

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