Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome

Analysis of virus replication on a single-cell level is often hampered by a lack of specific or sensitive enough reagents. Here, Douamet al. use RNA-flow technique to track (+) and (−) strand RNA of yellow fever virus in hematopoietic cells in mouse models and identify virus-host interactions that a...

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Bibliographic Details
Main Authors: Florian Douam, Gabriela Hrebikova, Yentli E. Soto Albrecht, Julie Sellau, Yael Sharon, Qiang Ding, Alexander Ploss
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/9e697919b38849b796bf1377f8eb6d31
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